Myosin post-translational modifications and function in the presence of myopathy-linked truncating MYH2 mutations

Keyphrases

• Acetylated Lysine 25%
• Actomyosin 25%
• Actomyosin Complex 25%
• ATP Consumption 25%
• ATP Synthase 25%
• Cellular Force 25%
• Cellular Mechanisms 25%
• Congenital Myopathy 25%
• Force Production 25%
• Genetic Defects 25%
• Genetic muscle Disease 25%
• Healthy Controls 25%
• Human Adult 25%
• In Vitro Motility Assay 25%
• Liquid Chromatography-tandem Mass Spectrometry (LC-MS/MS) 25%
• Mant-ATP 25%
• Molecular Mechanism 25%
• Muscle Fiber 50%
• Muscle Symptoms 25%
• Mutation Impact 25%
• MYH2 100%
• Myofiber 50%
• Myopathic 50%
• Myopathy 100%
• Myosin 100%
• Myosin Activation 25%
• Myosin Head 25%
• Myosin Heavy Chain (MyHC) 100%
• Myosin Molecule 25%
• Post-translational Modification 100%
• Skeletal muscle 25%
• Truncating mutation 50%

Biochemistry, Genetics and Molecular Biology

• Adenosine Triphosphate 75%
• ATPase 25%
• Conformation 50%
• Genetics 50%
• Heavy Meromyosin 100%
• Lysine 25%
• Myosin ATPase 50%
• Myosin Head 25%
• Normal Human 25%
• Posttranslational Modification 100%
• Skeletal Muscle 25%

Pharmacology, Toxicology and Pharmaceutical Science

• Adenosine Triphosphatase 25%
• Adenosine Triphosphate 75%
• Genetic Disorder 25%
• Lysine 25%
• Muscle Disease 25%
• Myopathy 100%
• Myosin Adenosine Triphosphatase 50%
• Myosin Heavy Chain 100%
• Normal Human 25%
• Symptom 25%