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Region Hovedstaden - en del af Københavns Universitetshospital
Udgivet

Myocardial strain analysis by 2-dimensional speckle tracking echocardiography improves diagnostics of coronary artery stenosis in stable angina pectoris

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  1. Patient-Specific Computer Simulation of Transcatheter Aortic Valve Replacement in Bicuspid Aortic Valve Morphology

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  2. Echocardiographic Predictors of Mortality in Women With Heart Failure With Reduced Ejection Fraction

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  3. Left Atrial Function in Heart Failure With Reduced Ejection Fraction

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  4. Prognostic Importance of Left Ventricular Mechanical Dyssynchrony in Predicting Cardiovascular Death in the General Population

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  1. Level of Physical Activity, Left Ventricular Mass, Hypertension, and Prognosis

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  2. Cardiovascular and metabolic health effects of team handball training in overweight women: Impact of prior experience

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  3. Catheter ablation for atrial fibrillation is associated with lower incidence of heart failure and death

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Background- Two-dimensional strain echocardiography detects early signs of left ventricular dysfunction; however, it is unknown whether myocardial strain analysis at rest in patients with suspected stable angina pectoris predicts the presence of coronary artery disease (CAD). Methods and Results- In total, 296 consecutive patients with clinically suspected stable angina pectoris, no previous cardiac history, and normal left ventricular ejection fraction were included. All patients were examined by 2-dimensional strain echocardiography, exercise ECG, and coronary angiography. Two-dimensional strain echocardiography was performed in the 3 apical projections. Peak regional longitudinal systolic strain was measured in 18 myocardial sites and averaged to provide global longitudinal peak systolic strain. Duke score, including ST-segment depression, chest pain, and exercise capacity, was used as the outcome of the exercise test. Patients with an area stenosis ≥70% in ≥1 epicardial coronary artery were categorized as having significant CAD (n=107). Global longitudinal peak systolic strain was significantly lower in patients with CAD compared with patients without (17.1±2.5% versus 18.8±2.6%; P
OriginalsprogEngelsk
TidsskriftCirculation. Cardiovascular Imaging
Vol/bind7
Udgave nummer1
Sider (fra-til)58-65
Antal sider8
ISSN1941-9651
DOI
StatusUdgivet - 1 jan. 2014

ID: 42631709