Mycobacterium brisbanense lung infection facilitated by steroid induced adrenal insufficiency

Rosa Gynthersen; Tavs Qvist; Åse B Andersen; Terese L Katzenstein

doi:10.1111/apm.12911

Mycobacterium brisbanense lung infection facilitated by steroid induced adrenal insufficiency

Rosa Gynthersen, Tavs Qvist, Åse B Andersen, Terese L Katzenstein

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Abstract

Mycobacterium brisbanense is rapid-growing nontuberculous mycobacteria. It was first described in 2004 as a human pathogen and only one case report has previously been published. We report a case of M. brisbanense infection in a young man with asthma, recurrent lung infections and secondary adrenal insufficiency induced by inhalation steroids and itraconazole use. The mycobacterial infection was successfully treated with a long-term multidrug regimen.

Originalsprog	Engelsk
Tidsskrift	APMIS - Journal of Pathology, Microbiology and Immunology
Vol/bind	127
Udgave nummer	2
Sider (fra-til)	106-108
Antal sider	3
ISSN	0903-4641
DOI	https://doi.org/10.1111/apm.12911
Status	Udgivet - 2019

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10.1111/apm.12911

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title = "Mycobacterium brisbanense lung infection facilitated by steroid induced adrenal insufficiency",

abstract = "Mycobacterium brisbanense is rapid-growing nontuberculous mycobacteria. It was first described in 2004 as a human pathogen and only one case report has previously been published. We report a case of M. brisbanense infection in a young man with asthma, recurrent lung infections and secondary adrenal insufficiency induced by inhalation steroids and itraconazole use. The mycobacterial infection was successfully treated with a long-term multidrug regimen.",

keywords = "Adrenal insufficiency, Mycobacterium brisbanense, nontuberculous mycobacteria, pulmonary infection, Humans, Moxifloxacin/therapeutic use, Male, Nontuberculous Mycobacteria/isolation & purification, Clarithromycin/therapeutic use, Adrenal Insufficiency/pathology, Mycobacterium Infections, Nontuberculous/drug therapy, Sputum/microbiology, Adult, Respiratory Tract Infections/drug therapy, Drug Therapy, Combination, Anti-Bacterial Agents/therapeutic use, Amikacin/therapeutic use",

author = "Rosa Gynthersen and Tavs Qvist and Andersen, {{\AA}se B} and Katzenstein, {Terese L}",

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doi = "10.1111/apm.12911",

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volume = "127",

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T1 - Mycobacterium brisbanense lung infection facilitated by steroid induced adrenal insufficiency

AU - Gynthersen, Rosa

AU - Qvist, Tavs

AU - Andersen, Åse B

AU - Katzenstein, Terese L

PY - 2019

Y1 - 2019

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AB - Mycobacterium brisbanense is rapid-growing nontuberculous mycobacteria. It was first described in 2004 as a human pathogen and only one case report has previously been published. We report a case of M. brisbanense infection in a young man with asthma, recurrent lung infections and secondary adrenal insufficiency induced by inhalation steroids and itraconazole use. The mycobacterial infection was successfully treated with a long-term multidrug regimen.

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KW - Mycobacterium brisbanense

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KW - pulmonary infection

KW - Humans

KW - Moxifloxacin/therapeutic use

KW - Male

KW - Nontuberculous Mycobacteria/isolation & purification

KW - Clarithromycin/therapeutic use

KW - Adrenal Insufficiency/pathology

KW - Mycobacterium Infections, Nontuberculous/drug therapy

KW - Sputum/microbiology

KW - Adult

KW - Respiratory Tract Infections/drug therapy

KW - Drug Therapy, Combination

KW - Anti-Bacterial Agents/therapeutic use

KW - Amikacin/therapeutic use

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U2 - 10.1111/apm.12911

DO - 10.1111/apm.12911

M3 - Journal article

C2 - 30585355

SN - 0903-4641

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SP - 106

EP - 108

JO - APMIS - Journal of Pathology, Microbiology and Immunology

JF - APMIS - Journal of Pathology, Microbiology and Immunology

IS - 2

ER -

Mycobacterium brisbanense lung infection facilitated by steroid induced adrenal insufficiency

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