@article{f67f9250ac3c46dfb4eb77e666c36b22,
title = "Mutations in sodium channel β-subunit SCN3B are associated with early-onset lone atrial fibrillation",
abstract = "Atrial fibrillation (AF) is the most frequent arrhythmia. Screening of SCN5A-the gene encoding the α-subunit of the cardiac sodium channel-has indicated that disturbances of the sodium current may play a central role in the mechanism of lone AF. We tested the hypothesis that lone AF in young patients is associated with genetic mutations in SCN3B and SCN4B, the genes encoding the two β-subunits of the cardiac sodium channel.",
keywords = "Adolescent, Adult, Atrial Fibrillation, Cohort Studies, Female, Humans, Male, Mutation, Polymerase Chain Reaction, Protein Subunits, Sodium Channels",
author = "Olesen, {Morten S} and Thomas Jespersen and Nielsen, {Jonas B} and Bo Liang and M{\o}ller, {Daniel V} and Paula Hedley and Michael Christiansen and Andr{\'a}s Varr{\'o} and S{\o}ren-Peter Olesen and Stig Hauns{\o} and Nicole Schmitt and Svendsen, {Jesper H}",
year = "2011",
doi = "10.1093/cvr/cvq348",
language = "English",
volume = "89",
pages = "786--93",
journal = "Cardiovascular Research",
issn = "0008-6363",
publisher = "Oxford University Press",
number = "4",
}