Mutation in APOA1 predicts increased risk of ischaemic heart disease and total mortality without low HDL cholesterol levels

C L Haase; R Frikke-Schmidt; B G Nordestgaard; A K Kateifides; D Kardassis; Lars Bo Nielsen; C B Andersen; L Køber; Anders Holten Johnsen; P Grande; V I Zannis; Anne Tybjærg-Hansen

doi:10.1111/j.1365-2796.2011.02381.x

Mutation in APOA1 predicts increased risk of ischaemic heart disease and total mortality without low HDL cholesterol levels

C L Haase, R Frikke-Schmidt, B G Nordestgaard, A K Kateifides, D Kardassis, Lars Bo Nielsen, C B Andersen, L Køber, Anders Holten Johnsen, P Grande, V I Zannis, Anne Tybjærg-Hansen

36 Citationer (Scopus)

Abstract

To determine whether mutations in APOA1 affect levels of high-density lipoprotein (HDL) cholesterol and to predict risk of ischaemic heart disease (IHD) and total mortality in the general population.

Originalsprog	Engelsk
Tidsskrift	Journal of Internal Medicine
Vol/bind	270
Udgave nummer	2
Sider (fra-til)	136-46
Antal sider	11
ISSN	0954-6820
DOI	https://doi.org/10.1111/j.1365-2796.2011.02381.x
Status	Udgivet - 2011

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Haase, C. L., Frikke-Schmidt, R., Nordestgaard, B. G., Kateifides, A. K., Kardassis, D., Nielsen, L. B., Andersen, C. B., Køber, L., Johnsen, A. H., Grande, P., Zannis, V. I., & Tybjærg-Hansen, A. (2011). Mutation in APOA1 predicts increased risk of ischaemic heart disease and total mortality without low HDL cholesterol levels. Journal of Internal Medicine, 270(2), 136-46. https://doi.org/10.1111/j.1365-2796.2011.02381.x

Haase, CL, Frikke-Schmidt, R , Nordestgaard, BG, Kateifides, AK, Kardassis, D, Nielsen, LB, Andersen, CB, Køber, L, Johnsen, AH, Grande, P, Zannis, VI & Tybjærg-Hansen, A 2011, 'Mutation in APOA1 predicts increased risk of ischaemic heart disease and total mortality without low HDL cholesterol levels', Journal of Internal Medicine, bind 270, nr. 2, s. 136-46. https://doi.org/10.1111/j.1365-2796.2011.02381.x

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title = "Mutation in APOA1 predicts increased risk of ischaemic heart disease and total mortality without low HDL cholesterol levels",

abstract = "To determine whether mutations in APOA1 affect levels of high-density lipoprotein (HDL) cholesterol and to predict risk of ischaemic heart disease (IHD) and total mortality in the general population.",

keywords = "Adult, Aged, Animals, Apolipoprotein A-I, Case-Control Studies, Denmark, Female, Humans, Lipoproteins, HDL, Male, Mice, Middle Aged, Mutation, Myocardial Ischemia, Risk Factors, Sequence Analysis, DNA, Survival Analysis",

author = "Haase, \{C L\} and R Frikke-Schmidt and Nordestgaard, \{B G\} and Kateifides, \{A K\} and D Kardassis and Nielsen, \{Lars Bo\} and Andersen, \{C B\} and L K{\o}ber and Johnsen, \{Anders Holten\} and P Grande and Zannis, \{V I\} and Anne Tybj{\ae}rg-Hansen",

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doi = "10.1111/j.1365-2796.2011.02381.x",

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T1 - Mutation in APOA1 predicts increased risk of ischaemic heart disease and total mortality without low HDL cholesterol levels

AU - Haase, C L

AU - Frikke-Schmidt, R

AU - Nordestgaard, B G

AU - Kateifides, A K

AU - Kardassis, D

AU - Nielsen, Lars Bo

AU - Andersen, C B

AU - Køber, L

AU - Johnsen, Anders Holten

AU - Grande, P

AU - Zannis, V I

AU - Tybjærg-Hansen, Anne

PY - 2011

Y1 - 2011

N2 - To determine whether mutations in APOA1 affect levels of high-density lipoprotein (HDL) cholesterol and to predict risk of ischaemic heart disease (IHD) and total mortality in the general population.

AB - To determine whether mutations in APOA1 affect levels of high-density lipoprotein (HDL) cholesterol and to predict risk of ischaemic heart disease (IHD) and total mortality in the general population.

KW - Adult

KW - Aged

KW - Animals

KW - Apolipoprotein A-I

KW - Case-Control Studies

KW - Denmark

KW - Female

KW - Humans

KW - Lipoproteins, HDL

KW - Male

KW - Mice

KW - Middle Aged

KW - Mutation

KW - Myocardial Ischemia

KW - Risk Factors

KW - Sequence Analysis, DNA

KW - Survival Analysis

UR - https://www.scopus.com/pages/publications/79960241608

U2 - 10.1111/j.1365-2796.2011.02381.x

DO - 10.1111/j.1365-2796.2011.02381.x

M3 - Journal article

C2 - 21443680

SN - 0954-6820

VL - 270

SP - 136

EP - 146

JO - Journal of Internal Medicine

JF - Journal of Internal Medicine

IS - 2

ER -

Mutation in APOA1 predicts increased risk of ischaemic heart disease and total mortality without low HDL cholesterol levels

Abstract

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