Forskning
Udskriv Udskriv
Switch language
Region Hovedstaden - en del af Københavns Universitetshospital
Udgivet

Multispectral imaging of hand eczema

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

DOI

  1. Allergic contact stomatitis caused by (meth)acrylates in an occlusal splint

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Identification of pigments related to allergic tattoo reactions in 104 human skin biopsies

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Exposure analysis using X-ray fluorescence device and a cobalt spot test in four patients with cobalt allergy

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  4. Causative exposures and temporal development of cobalt allergy in Denmark between 2002 and 2017

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  5. Diagnostic workup of occupational allergic nickel dermatitis in a nurse with multiple nickel exposures

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. Allergic contact stomatitis caused by (meth)acrylates in an occlusal splint

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Exposure analysis using X-ray fluorescence device and a cobalt spot test in four patients with cobalt allergy

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Systematic review on rapidity of onset of action for interleukin-17 and interleukin-23 inhibitors for psoriasis

    Publikation: Bidrag til tidsskriftReviewForskningpeer review

  4. Interaction between filaggrin mutations and neonatal cat exposure in atopic dermatitis

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Vis graf over relationer

BACKGROUND: Hand eczema is a disease with large variation in clinical presentation and severity. Scoring systems for quantitative severity assessment exist. However, they are observer-dependent. An objective quantitative tool for scoring of hand eczema would improve categorization of hand eczema.

OBJECTIVE: To investigate the usefulness of multispectral imaging in assessing severity of hand eczema with respect to extent and the different morphological features.

METHODS: Patients with hand eczema (n = 60) and healthy controls (n = 28) were included. The severity of hand eczema was assessed by a dermatologist using the Hand Eczema Severity Index (HECSI) and a global assessment (Physician Global Assessment [PGA]). Multispectral imaging of the hand was performed on all patients and controls using the VideometerLab Instrument.

RESULTS: Areas of the morphological elements identified by multispectral imaging were statistically significantly correlated with the PGA scores. Analyzed by Cohen's kappa, a moderate agreement between imaging-based severity assessment and PGA was found. The imaging-based severity assessment was also correlated with HECSI (Spearman rho 0.683, P < .001). Still, the imaging-based algorithm was not capable of differentiating hand eczema patients from controls.

CONCLUSIONS: Multispectral imaging allows quantitative measurements of different skin parameters to be performed. In its present form, multispectral imaging cannot replace the clinical assessment of a dermatologist. However, after refinement, this or similar technologies could prove useful.

OriginalsprogEngelsk
TidsskriftContact Dermatitis
Vol/bind81
Udgave nummer6
Sider (fra-til)438-445
Antal sider8
ISSN0105-1873
DOI
StatusUdgivet - dec. 2019

Bibliografisk note

© 2019 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

ID: 58983090