Multifocality as a prognostic factor in breast cancer patients registered in Danish Breast Cancer Cooperative Group (DBCG) 1996-2001

L E Joergensen; K A Gunnarsdottir; C Lanng; S Moeller; B B Rasmussen

doi:10.1016/j.breast.2008.06.004

Multifocality as a prognostic factor in breast cancer patients registered in Danish Breast Cancer Cooperative Group (DBCG) 1996-2001

L E Joergensen, K A Gunnarsdottir, C Lanng, S Moeller, B B Rasmussen

50 Citationer (Scopus)

Abstract

The purpose of this study was to investigate the prognostic influence of multifocality in breast cancer patients. In a cohort of 7196 patients there were 945 patients with multifocality. We found no prognostic influence of multifocality on overall survival when controlling for known prognostic factors. We found a small but significant influence on disease-free survival (HR=1.16 [1.03-1.31]) and a strong correlation between multifocality and known prognostic factors. This was in accordance with an earlier study done on a smaller population and in a different period of time [Pedersen L, Gunnarsdottir KA, Rasmussen BB, Moeller S, Lanng C. The prognostic influence of multifocality in breast cancer patients. Breast 2004;13:188-193].

Originalsprog	Engelsk
Tidsskrift	Breast
Vol/bind	17
Udgave nummer	6
Sider (fra-til)	587-91
Antal sider	5
ISSN	0960-9776
DOI	https://doi.org/10.1016/j.breast.2008.06.004
Status	Udgivet - 1 dec. 2008

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10.1016/j.breast.2008.06.004

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title = "Multifocality as a prognostic factor in breast cancer patients registered in Danish Breast Cancer Cooperative Group (DBCG) 1996-2001",

abstract = "The purpose of this study was to investigate the prognostic influence of multifocality in breast cancer patients. In a cohort of 7196 patients there were 945 patients with multifocality. We found no prognostic influence of multifocality on overall survival when controlling for known prognostic factors. We found a small but significant influence on disease-free survival (HR=1.16 [1.03-1.31]) and a strong correlation between multifocality and known prognostic factors. This was in accordance with an earlier study done on a smaller population and in a different period of time [Pedersen L, Gunnarsdottir KA, Rasmussen BB, Moeller S, Lanng C. The prognostic influence of multifocality in breast cancer patients. Breast 2004;13:188-193].",

keywords = "Adult, Age Distribution, Aged, Breast Neoplasms, Chi-Square Distribution, Cohort Studies, Denmark, Female, Humans, Menopause, Middle Aged, Multivariate Analysis, Neoplasms, Multiple Primary, Prognosis, Proportional Hazards Models, Registries, Retrospective Studies, Survival Analysis",

author = "Joergensen, \{L E\} and Gunnarsdottir, \{K A\} and C Lanng and S Moeller and Rasmussen, \{B B\}",

year = "2008",

month = dec,

day = "1",

doi = "10.1016/j.breast.2008.06.004",

language = "English",

volume = "17",

pages = "587--91",

journal = "Breast",

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TY - JOUR

T1 - Multifocality as a prognostic factor in breast cancer patients registered in Danish Breast Cancer Cooperative Group (DBCG) 1996-2001

AU - Joergensen, L E

AU - Gunnarsdottir, K A

AU - Lanng, C

AU - Moeller, S

AU - Rasmussen, B B

PY - 2008/12/1

Y1 - 2008/12/1

N2 - The purpose of this study was to investigate the prognostic influence of multifocality in breast cancer patients. In a cohort of 7196 patients there were 945 patients with multifocality. We found no prognostic influence of multifocality on overall survival when controlling for known prognostic factors. We found a small but significant influence on disease-free survival (HR=1.16 [1.03-1.31]) and a strong correlation between multifocality and known prognostic factors. This was in accordance with an earlier study done on a smaller population and in a different period of time [Pedersen L, Gunnarsdottir KA, Rasmussen BB, Moeller S, Lanng C. The prognostic influence of multifocality in breast cancer patients. Breast 2004;13:188-193].

AB - The purpose of this study was to investigate the prognostic influence of multifocality in breast cancer patients. In a cohort of 7196 patients there were 945 patients with multifocality. We found no prognostic influence of multifocality on overall survival when controlling for known prognostic factors. We found a small but significant influence on disease-free survival (HR=1.16 [1.03-1.31]) and a strong correlation between multifocality and known prognostic factors. This was in accordance with an earlier study done on a smaller population and in a different period of time [Pedersen L, Gunnarsdottir KA, Rasmussen BB, Moeller S, Lanng C. The prognostic influence of multifocality in breast cancer patients. Breast 2004;13:188-193].

KW - Adult

KW - Age Distribution

KW - Aged

KW - Breast Neoplasms

KW - Chi-Square Distribution

KW - Cohort Studies

KW - Denmark

KW - Female

KW - Humans

KW - Menopause

KW - Middle Aged

KW - Multivariate Analysis

KW - Neoplasms, Multiple Primary

KW - Prognosis

KW - Proportional Hazards Models

KW - Registries

KW - Retrospective Studies

KW - Survival Analysis

UR - https://www.scopus.com/pages/publications/56949100368

U2 - 10.1016/j.breast.2008.06.004

DO - 10.1016/j.breast.2008.06.004

M3 - Journal article

C2 - 18691887

SN - 0960-9776

VL - 17

SP - 587

EP - 591

JO - Breast

JF - Breast

IS - 6

ER -

Multifocality as a prognostic factor in breast cancer patients registered in Danish Breast Cancer Cooperative Group (DBCG) 1996-2001

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