Abstract
Neuromuscular blockers (NMBs) provide good conditions for endotracheal intubation and surgery. NMBs have been associated with higher morbidity and mortality, mainly due to post-operative residual neuromuscular block. This may become history with the advent of sugammadex - an antidote to the NMB rocuronium - which within 1-3 minutes neutralizes the effects of rocuronium. High-dose rocuronium is now an alternative to suxamethonium in acute or short procedures and in a situation, where ventilation/intubating cannot be performed, sugammadex can reverse the rocuronium blockade within minutes.
| Bidragets oversatte titel | Possible clinical potential in reverting muscular block with sugammadex in anaesthesia and surgery |
|---|---|
| Originalsprog | Dansk |
| Tidsskrift | Ugeskrift for Laeger |
| Vol/bind | 175 |
| Udgave nummer | 7 |
| Sider (fra-til) | 428-32 |
| Antal sider | 5 |
| ISSN | 0041-5782 |
| Status | Udgivet - 11 feb. 2013 |
Emneord
- Androstanols
- Anesthesia
- Anesthesia Recovery Period
- Humans
- Intubation, Intratracheal
- Neostigmine
- Neuromuscular Blockade
- Neuromuscular Nondepolarizing Agents
- Time Factors
- gamma-Cyclodextrins