TY - JOUR
T1 - MTHFR C677T genotype and cardiovascular risk in a general population without mandatory folic acid fortification
AU - Husemoen, Lise Lotte N
AU - Skaaby, Tea
AU - Jørgensen, Torben
AU - Thuesen, Betina H
AU - Fenger, Mogens
AU - Grarup, Niels
AU - Sandholt, Camilla Helene
AU - Hansen, Torben
AU - Pedersen, Oluf Borbye
AU - Linneberg, Allan
PY - 2014/1/24
Y1 - 2014/1/24
N2 - Meta-analyses have suggested an effect of MTHFR C677T genotype (rs1801133), a proxy for blood total homocysteine, on cardiovascular disease (CVD) in populations with low population dietary folate. The aim was to examine the association and effect modification by serum folate and vitamin B12 levels between MTHFR and CVD-related outcomes in a general population with no mandatory folic acid fortification policy.
AB - Meta-analyses have suggested an effect of MTHFR C677T genotype (rs1801133), a proxy for blood total homocysteine, on cardiovascular disease (CVD) in populations with low population dietary folate. The aim was to examine the association and effect modification by serum folate and vitamin B12 levels between MTHFR and CVD-related outcomes in a general population with no mandatory folic acid fortification policy.
U2 - 10.1007/s00394-014-0659-2
DO - 10.1007/s00394-014-0659-2
M3 - Journal article
C2 - 24458267
SN - 1436-6207
VL - 53
SP - 1549
EP - 1559
JO - European Journal of Nutrition
JF - European Journal of Nutrition
IS - 7
ER -