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Mortality among hip fracture patients infected with COVID-19 perioperatively

Publikation: Bidrag til tidsskriftReviewForskningpeer review

DOI

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  2. Thyroid-stimulating hormone (TSH) is associated with 30-day mortality in hip fracture patients

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BACKGROUND AND PURPOSE: The outbreak of the COVID-19 pandemic has resulted in an overall decline in fractures. However, the amount of hip fractures has remained relatively stable throughout the period. The objective of this study is to investigate the impact of perioperative COVID-19 infections on mortality among hip fracture patients.

METHODS: A meta-analysis was performed by collecting current data available through a systematic literature search in the PubMed database. The search was performed Oct 18 2020.

RESULTS: The meta-analysis was conducted on a trial population consisting of 1.272 hip fracture patients with a pooled prevalence of COVID-19 of 18%. Mortality among hip fracture patients without a perioperative COVID-19 infection was 7.49%. Mortality among hip fracture patients infected with COVID-19 perioperatively was associated with an odds ratio of 6.70 [(95% CI 4.64-9.68), p < 0.00001, I2 = 41%]. A sensitivity analysis showed no major impact of assumptions regarding varying definitions of COVID-19 statuses among the included studies.

CONCLUSION: Perioperative infections with COVID-19 in hip fracture patients are correlated with a significantly increased mortality. The meta-analysis showed a pooled odds ratio of 6.70 [(95% CI 4.64-9.68), p < 0.00001, I2 = 41%].

OriginalsprogEngelsk
TidsskriftEuropean journal of trauma and emergency surgery : official publication of the European Trauma Society
Vol/bind47
Udgave nummer3
Sider (fra-til)659-664
Antal sider6
ISSN1863-9933
DOI
StatusUdgivet - jun. 2021

ID: 64228817