Molekylaer patogenese ved monogen og polygen fedme

Philip J Larsen, Søren M Echwald, Thorkild I A Sørensen, Oluf Borbye Pedersen

    1 Citationer (Scopus)

    Abstract

    During the last few years, studies of the molecular pathogenesis of obesity both in mouse models and in the rare cases of monogenic obesity in humans have added significantly to our understanding of the key role of the hypothalamus in mediating hunger and satiety. These insights have brought us closer to the development of rational therapies of obesity, the epidemic of which is continuing in the post-industrial society, which is characterised by sedentary behaviour patterns.

    Bidragets oversatte titelMolecular pathogenesis in monogenic and polygenic obesity
    OriginalsprogDansk
    TidsskriftUgeskrift for Laeger
    Vol/bind168
    Udgave nummer2
    Sider (fra-til)152-5
    Antal sider4
    ISSN0041-5782
    StatusUdgivet - 9 jan. 2006

    Emneord

    • Animals
    • Appetite
    • Humans
    • Hypothalamus
    • Mice
    • Obesity
    • Receptors, Cell Surface
    • Receptors, Leptin
    • Satiation

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