Modulation of the sodium-chloride cotransporter by insulin in auditory cells: A potential link to diabetes-related hearing complications

Keyphrases

• Diabetes 100%
• Insulin 100%
• Phosphorylation 100%
• Sodium-chloride Cotransporter 100%
• Auditory Neurons 100%
• Signaling Pathway 37%
• Ceramide 37%
• Insulin Signaling 37%
• Protein Kinase 25%
• Protein Kinase B 25%
• HEI-OC1 Cells 25%
• With-no-lysine Kinase 25%
• Phosphatidylinositol 3-kinase/protein Kinase B 25%
• Serum/glucocorticoid Regulated Kinase 1 25%
• Upstream Signaling 25%
• Western Blot Analysis 12%
• Insulin Therapy 12%
• Insulin Resistance 12%
• Wortmannin 12%
• Phosphatidylinositol 3-kinase Inhibitor 12%
• Vestibular Function 12%
• Downstream Targets 12%
• Inner Ear 12%
• Diabetes Mellitus Type 2 12%
• Kinase Inhibitor 12%
• Signal Component 12%
• Epithelial Sodium Channel (ENaC) 12%
• Diabetes Mellitus Type 1 12%
• Saccule 12%
• Auditory Function 12%
• Protein Kinase A Signaling 12%
• Sodium Homeostasis 12%
• Sodium Transporters 12%
• MK-2206 12%
• NDRG1 12%
• GSK650394 12%
• Dose-dependent 12%
• Inner Ear Disease 12%

Neuroscience

• Sensation of Hearing 100%
• Insulin 100%
• Sodium Chloride Cotransporter 100%
• phosphorylation 88%
• Protein Kinase B 44%
• Kinase 33%
• Cell Signaling 33%
• Insulin Signaling 33%
• Ceramide 33%
• Protein Kinase A 33%
• Glucocorticoid 22%
• Phosphoinositide 3-Kinase 22%
• Serine/Threonine Protein Kinase WNK1 22%
• Cyclic Adenosine Monophosphate 11%
• Diabetes Mellitus Type 1 11%
• Western Blot 11%
• Epithelial Sodium Channel 11%
• Saccule 11%
• H-89 11%
• Wortmannin 11%
• Phosphoinositide 3-Kinase Inhibitor 11%