Modeling freedom from progression for standard-risk medulloblastoma: a mathematical tumor control model with multiple modes of failure

N Patrik Brodin; Ivan R Vogelius; Thomas Björk-Eriksson; Per Munck af Rosenschöld; Søren M Bentzen

doi:10.1016/j.ijrobp.2013.06.008

Modeling freedom from progression for standard-risk medulloblastoma: a mathematical tumor control model with multiple modes of failure

N Patrik Brodin
, Ivan R Vogelius
, Thomas Björk-Eriksson
, Per Munck af Rosenschöld
, Søren M Bentzen

6 Citationer (Scopus)

Abstract

As pediatric medulloblastoma (MB) is a relatively rare disease, it is important to extract the maximum information from trials and cohort studies. Here, a framework was developed for modeling tumor control with multiple modes of failure and time-to-progression for standard-risk MB, using published pattern of failure data.

Originalsprog	Engelsk
Tidsskrift	International Journal of Radiation: Oncology - Biology - Physics
Vol/bind	87
Udgave nummer	2
Sider (fra-til)	422-9
Antal sider	8
ISSN	0360-3016
DOI	https://doi.org/10.1016/j.ijrobp.2013.06.008
Status	Udgivet - 1 okt. 2013

Adgang til dokumentet

10.1016/j.ijrobp.2013.06.008

Citationsformater

Modeling freedom from progression for standard-risk medulloblastoma: a mathematical tumor control model with multiple modes of failure. / Brodin, N Patrik; Vogelius, Ivan R; Björk-Eriksson, Thomas et al.
I: International Journal of Radiation: Oncology - Biology - Physics, Bind 87, Nr. 2, 01.10.2013, s. 422-9.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

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abstract = "As pediatric medulloblastoma (MB) is a relatively rare disease, it is important to extract the maximum information from trials and cohort studies. Here, a framework was developed for modeling tumor control with multiple modes of failure and time-to-progression for standard-risk MB, using published pattern of failure data.",

keywords = "Algorithms, Cerebellar Neoplasms, Child, Disease-Free Survival, Dose-Response Relationship, Radiation, Humans, Medulloblastoma, Models, Biological, Monte Carlo Method, Neoplasm Recurrence, Local, Rare Diseases, Treatment Failure, Uncertainty",

author = "Brodin, \{N Patrik\} and Vogelius, \{Ivan R\} and Thomas Bj{\"o}rk-Eriksson and \{Munck af Rosensch{\"o}ld\}, Per and Bentzen, \{S{\o}ren M\}",

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doi = "10.1016/j.ijrobp.2013.06.008",

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AU - Brodin, N Patrik

AU - Vogelius, Ivan R

AU - Björk-Eriksson, Thomas

AU - Munck af Rosenschöld, Per

AU - Bentzen, Søren M

PY - 2013/10/1

Y1 - 2013/10/1

N2 - As pediatric medulloblastoma (MB) is a relatively rare disease, it is important to extract the maximum information from trials and cohort studies. Here, a framework was developed for modeling tumor control with multiple modes of failure and time-to-progression for standard-risk MB, using published pattern of failure data.

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KW - Algorithms

KW - Cerebellar Neoplasms

KW - Child

KW - Disease-Free Survival

KW - Dose-Response Relationship, Radiation

KW - Humans

KW - Medulloblastoma

KW - Models, Biological

KW - Monte Carlo Method

KW - Neoplasm Recurrence, Local

KW - Rare Diseases

KW - Treatment Failure

KW - Uncertainty

U2 - 10.1016/j.ijrobp.2013.06.008

DO - 10.1016/j.ijrobp.2013.06.008

M3 - Journal article

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SP - 422

EP - 429

JO - International Journal of Radiation: Oncology - Biology - Physics

JF - International Journal of Radiation: Oncology - Biology - Physics

IS - 2

ER -

Modeling freedom from progression for standard-risk medulloblastoma: a mathematical tumor control model with multiple modes of failure

Abstract

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