Mitochondrial 12S Ribosomal RNA A1555G Mutation Associated with Cardiomyopathy and Hearing Loss following High-Dose Chemotherapy and Repeated Aminoglycoside Exposure

Anne-Sofie Skou, Lisbeth Tranebjærg, Tim Jensen, Henrik Hasle

12 Citationer (Scopus)

Abstract

A 19-month-old girl with the A1555G mitochondrial mutation in the 12S ribosomal RNA gene and acute myelogenous leukemia developed dilated cardiomyopathy and bilateral sensorineural hearing loss before undergoing allogeneic stem cell transplantation. She had received gentamicin during episodes of febrile neutropenia. Testing for the A1555G mutation is recommended in patients frequently treated with aminoglycosides.
OriginalsprogEngelsk
TidsskriftThe Journal of pediatrics
Vol/bind164
Udgave nummer2
Sider (fra-til)413-15
ISSN0022-3476
DOI
StatusUdgivet - 2014

Fingeraftryk

Dyk ned i forskningsemnerne om 'Mitochondrial 12S Ribosomal RNA A1555G Mutation Associated with Cardiomyopathy and Hearing Loss following High-Dose Chemotherapy and Repeated Aminoglycoside Exposure'. Sammen danner de et unikt fingeraftryk.

Citationsformater