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Minimally important differences for interpreting European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 scores in patients with head and neck cancer

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Harvard

Musoro, JZ, Coens, C, Singer, S, Tribius, S, Oosting, SF, Groenvold, M, Simon, C, Machiels, J-P, Grégoire, V, Velikova, G, Cocks, K, Sprangers, MAG, King, MT & Bottomley, A 2020, 'Minimally important differences for interpreting European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 scores in patients with head and neck cancer', Head and Neck, bind 42, nr. 11, s. 3141-3152. https://doi.org/10.1002/hed.26363

APA

Musoro, J. Z., Coens, C., Singer, S., Tribius, S., Oosting, S. F., Groenvold, M., Simon, C., Machiels, J-P., Grégoire, V., Velikova, G., Cocks, K., Sprangers, M. A. G., King, M. T., & Bottomley, A. (2020). Minimally important differences for interpreting European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 scores in patients with head and neck cancer. Head and Neck, 42(11), 3141-3152. https://doi.org/10.1002/hed.26363

CBE

Musoro JZ, Coens C, Singer S, Tribius S, Oosting SF, Groenvold M, Simon C, Machiels J-P, Grégoire V, Velikova G, Cocks K, Sprangers MAG, King MT, Bottomley A. 2020. Minimally important differences for interpreting European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 scores in patients with head and neck cancer. Head and Neck. 42(11):3141-3152. https://doi.org/10.1002/hed.26363

MLA

Vancouver

Author

Musoro, Jammbe Z ; Coens, Corneel ; Singer, Susanne ; Tribius, Silke ; Oosting, Sjoukje F ; Groenvold, Mogens ; Simon, Christian ; Machiels, Jean-Pascal ; Grégoire, Vincent ; Velikova, Galina ; Cocks, Kim ; Sprangers, Mirjam A G ; King, Madeleine T ; Bottomley, Andrew. / Minimally important differences for interpreting European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 scores in patients with head and neck cancer. I: Head and Neck. 2020 ; Bind 42, Nr. 11. s. 3141-3152.

Bibtex

@article{f4704f75c5ba45af96f65f0d418b9674,
title = "Minimally important differences for interpreting European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 scores in patients with head and neck cancer",
abstract = "BACKGROUND: We aimed to estimate minimally important difference (MID) for interpreting group-level change over time for European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire core 30 (EORTC QLQ-C30) scores in head and neck cancer.METHODS: Data were derived retrospectively from two published EORTC trials. Clinical anchors were selected using correlation strength and clinical plausibility of the given anchor/QLQ-C30 scale pair. MIDs for within-group and between-group change were estimated via the mean change method and linear regression, respectively. Distribution-based MIDs were also examined. MIDs for two of the scales, dyspnea and nausea/vomiting, are more uncertain considering their low correlations with the anchors.RESULTS: Anchor-based MIDs could be determined for deterioration in 7 of the 14 QLQ-C30 scales assessed, and in 3 scales for improvement. MIDs varied by scale, direction of change, and anchor. Absolute MID values ranged from 5 to 15 points for within-group change and 4 to 12 for between-group change. Most MIDs were within 4 to 10 points.CONCLUSIONS: Our findings, if confirmed, will aid interpreting changes in selected QLQ-C30 scale scores over time and inform sample size calculations in future clinical trials in head and neck cancer.",
keywords = "EORTC QLQ-C30, head and neck cancer, health-related quality of life, minimally important difference",
author = "Musoro, {Jammbe Z} and Corneel Coens and Susanne Singer and Silke Tribius and Oosting, {Sjoukje F} and Mogens Groenvold and Christian Simon and Jean-Pascal Machiels and Vincent Gr{\'e}goire and Galina Velikova and Kim Cocks and Sprangers, {Mirjam A G} and King, {Madeleine T} and Andrew Bottomley",
note = "{\textcopyright} 2020 Wiley Periodicals LLC.",
year = "2020",
month = nov,
doi = "10.1002/hed.26363",
language = "English",
volume = "42",
pages = "3141--3152",
journal = "Head and Neck",
issn = "1043-3074",
publisher = "John/Wiley & Sons, Inc. John/Wiley & Sons Ltd",
number = "11",

}

RIS

TY - JOUR

T1 - Minimally important differences for interpreting European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 scores in patients with head and neck cancer

AU - Musoro, Jammbe Z

AU - Coens, Corneel

AU - Singer, Susanne

AU - Tribius, Silke

AU - Oosting, Sjoukje F

AU - Groenvold, Mogens

AU - Simon, Christian

AU - Machiels, Jean-Pascal

AU - Grégoire, Vincent

AU - Velikova, Galina

AU - Cocks, Kim

AU - Sprangers, Mirjam A G

AU - King, Madeleine T

AU - Bottomley, Andrew

N1 - © 2020 Wiley Periodicals LLC.

PY - 2020/11

Y1 - 2020/11

N2 - BACKGROUND: We aimed to estimate minimally important difference (MID) for interpreting group-level change over time for European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire core 30 (EORTC QLQ-C30) scores in head and neck cancer.METHODS: Data were derived retrospectively from two published EORTC trials. Clinical anchors were selected using correlation strength and clinical plausibility of the given anchor/QLQ-C30 scale pair. MIDs for within-group and between-group change were estimated via the mean change method and linear regression, respectively. Distribution-based MIDs were also examined. MIDs for two of the scales, dyspnea and nausea/vomiting, are more uncertain considering their low correlations with the anchors.RESULTS: Anchor-based MIDs could be determined for deterioration in 7 of the 14 QLQ-C30 scales assessed, and in 3 scales for improvement. MIDs varied by scale, direction of change, and anchor. Absolute MID values ranged from 5 to 15 points for within-group change and 4 to 12 for between-group change. Most MIDs were within 4 to 10 points.CONCLUSIONS: Our findings, if confirmed, will aid interpreting changes in selected QLQ-C30 scale scores over time and inform sample size calculations in future clinical trials in head and neck cancer.

AB - BACKGROUND: We aimed to estimate minimally important difference (MID) for interpreting group-level change over time for European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire core 30 (EORTC QLQ-C30) scores in head and neck cancer.METHODS: Data were derived retrospectively from two published EORTC trials. Clinical anchors were selected using correlation strength and clinical plausibility of the given anchor/QLQ-C30 scale pair. MIDs for within-group and between-group change were estimated via the mean change method and linear regression, respectively. Distribution-based MIDs were also examined. MIDs for two of the scales, dyspnea and nausea/vomiting, are more uncertain considering their low correlations with the anchors.RESULTS: Anchor-based MIDs could be determined for deterioration in 7 of the 14 QLQ-C30 scales assessed, and in 3 scales for improvement. MIDs varied by scale, direction of change, and anchor. Absolute MID values ranged from 5 to 15 points for within-group change and 4 to 12 for between-group change. Most MIDs were within 4 to 10 points.CONCLUSIONS: Our findings, if confirmed, will aid interpreting changes in selected QLQ-C30 scale scores over time and inform sample size calculations in future clinical trials in head and neck cancer.

KW - EORTC QLQ-C30

KW - head and neck cancer

KW - health-related quality of life

KW - minimally important difference

UR - http://www.scopus.com/inward/record.url?scp=85087454209&partnerID=8YFLogxK

U2 - 10.1002/hed.26363

DO - 10.1002/hed.26363

M3 - Journal article

C2 - 32627261

VL - 42

SP - 3141

EP - 3152

JO - Head and Neck

JF - Head and Neck

SN - 1043-3074

IS - 11

ER -

ID: 61353431