MicroRNA-130a-mediated down-regulation of Smad4 contributes to reduced sensitivity to TGF-β1 stimulation in granulocytic precursors

Keyphrases

• TGF-1 100%
• MicroRNA-130a 100%
• MiR-130a 100%
• SMAD4 100%
• Granulocytic 100%
• Reduction-sensitive 100%
• Smad4 Protein 40%
• Binding Site 20%
• Kasumi-1 20%
• Differentially Expressed 10%
• Low Expression 10%
• Growth Inhibition 10%
• A549 10%
• Cell Growth 10%
• Overexpression 10%
• Acute Myeloid Leukemia 10%
• 3′-untranslated Region (3′-UTR) 10%
• Transcriptional Activation 10%
• Cell Cycle Regulation 10%
• Induced Growth 10%
• Cell Growth Inhibition 10%
• Granulopoiesis 10%
• Antisense RNA 10%
• Neutrophil Maturation 10%
• Transcription Inhibition 10%
• Human Embryonic Kidney 293 (HEK293) 10%
• Antisense Probe 10%

Biochemistry, Genetics and Molecular Biology

• MicroRNA 100%
• Precursor 100%
• Downregulation 100%
• Messenger RNA 100%
• Smad4 Protein 80%
• Binding Site 40%
• Growth Inhibition 40%
• Cell Growth 40%
• Polymorphonuclear Cell 40%
• Maturation 20%
• Untranslated Region 20%
• Granulopoiesis 20%
• Transcription Initiation 20%
• Transactivation 20%
• Cell Cycle Regulation 20%
• Antisense RNA 20%
• RNA Probe 20%