Methylprednisolone prevents tumour necrosis factor-alpha-dependent multinucleated giant cell formation

Henrik Rasmus Maltesen; Claus H Nielsen; Christina Schjellerup Dalbøge; Bo Baslund

doi:10.1093/rheumatology/keq213

Methylprednisolone prevents tumour necrosis factor-alpha-dependent multinucleated giant cell formation

Henrik Rasmus Maltesen, Claus H Nielsen, Christina Schjellerup Dalbøge, Bo Baslund

7 Citationer (Scopus)

Abstrakt

Granulomas contain multinucleated giant cells (MGCs), the function of which remains largely unknown. In patients with autoimmune granulomatous disease, the granulomas can be resolved during treatment with glucocorticosteroid (GCS). However, little is known about the influence of GCSs on the formation of MGCs.

Originalsprog	Engelsk
Tidsskrift	Rheumatology (Oxford, England)
Vol/bind	49
Udgave nummer	11
Sider (fra-til)	2037-42
Antal sider	6
DOI	https://doi.org/10.1093/rheumatology/keq213
Status	Udgivet - 1 nov. 2010

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10.1093/rheumatology/keq213

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title = "Methylprednisolone prevents tumour necrosis factor-alpha-dependent multinucleated giant cell formation",

abstract = "Granulomas contain multinucleated giant cells (MGCs), the function of which remains largely unknown. In patients with autoimmune granulomatous disease, the granulomas can be resolved during treatment with glucocorticosteroid (GCS). However, little is known about the influence of GCSs on the formation of MGCs.",

author = "Maltesen, {Henrik Rasmus} and Nielsen, {Claus H} and Dalb{\o}ge, {Christina Schjellerup} and Bo Baslund",

year = "2010",

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doi = "10.1093/rheumatology/keq213",

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issn = "1462-0324",

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TY - JOUR

T1 - Methylprednisolone prevents tumour necrosis factor-alpha-dependent multinucleated giant cell formation

AU - Maltesen, Henrik Rasmus

AU - Nielsen, Claus H

AU - Dalbøge, Christina Schjellerup

AU - Baslund, Bo

PY - 2010/11/1

Y1 - 2010/11/1

N2 - Granulomas contain multinucleated giant cells (MGCs), the function of which remains largely unknown. In patients with autoimmune granulomatous disease, the granulomas can be resolved during treatment with glucocorticosteroid (GCS). However, little is known about the influence of GCSs on the formation of MGCs.

AB - Granulomas contain multinucleated giant cells (MGCs), the function of which remains largely unknown. In patients with autoimmune granulomatous disease, the granulomas can be resolved during treatment with glucocorticosteroid (GCS). However, little is known about the influence of GCSs on the formation of MGCs.

U2 - 10.1093/rheumatology/keq213

DO - 10.1093/rheumatology/keq213

M3 - Journal article

C2 - 20634232

VL - 49

SP - 2037

EP - 2042

JO - Rheumatology

JF - Rheumatology

SN - 1462-0324

IS - 11

ER -

Methylprednisolone prevents tumour necrosis factor-alpha-dependent multinucleated giant cell formation

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