TY - JOUR
T1 - Methodology of the Second Pediatric Acute Lung Injury Consensus Conference
AU - Iyer, Narayan
AU - Khemani, Robinder
AU - Emeriaud, Guillaume
AU - López-Fernández, Yolanda M
AU - Korang, Steven Kwasi
AU - Steffen, Katherine M
AU - Barbaro, Ryan P
AU - Bembea, Melania M
AU - Second Pediatric Acute Lung Injury Consensus Conference (PALICC-2) Group on behalf and the Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network
N1 - Copyright © 2023 by the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies.
PY - 2023/2/1
Y1 - 2023/2/1
N2 - OBJECTIVES: This article describes the methodology used for The Second Pediatric Acute Lung Injury Consensus Conference (PALICC-2). The PALLIC-2 sought to develop evidence-based clinical recommendations and when evidence was lacking, expert-based consensus statements and research priorities for the diagnosis and management of pediatric acute respiratory distress syndrome (PARDS).DATA SOURCES: Electronic searches were conducted using PubMed, Embase, and Cochrane Library (CENTRAL) databases from 2012 to March 2022.STUDY SELECTION: Content was divided into 11 sections related to PARDS, with abstract and full text screening followed by data extraction for studies which met inclusion with no exclusion criteria.DATA EXTRACTION: We used a standardized data extraction form to construct evidence tables, grade the evidence, and formulate recommendations or statements using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) system.DATA SYNTHESIS: This consensus conference was comprised of a multidisciplinary group of international experts in pediatric critical care, pulmonology, respiratory care, and implementation science which followed standards set by the Institute of Medicine, using the GRADE system and Research And Development/University of California, Los Angeles appropriateness method, modeled after PALICC 2015. The panel of 52 content and four methodology experts had several web-based meetings over the course of 2 years. We conducted seven systematic reviews and four scoping reviews to cover the 11 topic areas. Dissemination was via primary publication listing all statements and separate supplemental publications for each subtopic that include supporting arguments for each recommendation and statement.CONCLUSIONS: A consensus conference of experts from around the world developed recommendations and consensus statements for the definition and management of PARDS and identified evidence gaps which need further research.
AB - OBJECTIVES: This article describes the methodology used for The Second Pediatric Acute Lung Injury Consensus Conference (PALICC-2). The PALLIC-2 sought to develop evidence-based clinical recommendations and when evidence was lacking, expert-based consensus statements and research priorities for the diagnosis and management of pediatric acute respiratory distress syndrome (PARDS).DATA SOURCES: Electronic searches were conducted using PubMed, Embase, and Cochrane Library (CENTRAL) databases from 2012 to March 2022.STUDY SELECTION: Content was divided into 11 sections related to PARDS, with abstract and full text screening followed by data extraction for studies which met inclusion with no exclusion criteria.DATA EXTRACTION: We used a standardized data extraction form to construct evidence tables, grade the evidence, and formulate recommendations or statements using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) system.DATA SYNTHESIS: This consensus conference was comprised of a multidisciplinary group of international experts in pediatric critical care, pulmonology, respiratory care, and implementation science which followed standards set by the Institute of Medicine, using the GRADE system and Research And Development/University of California, Los Angeles appropriateness method, modeled after PALICC 2015. The panel of 52 content and four methodology experts had several web-based meetings over the course of 2 years. We conducted seven systematic reviews and four scoping reviews to cover the 11 topic areas. Dissemination was via primary publication listing all statements and separate supplemental publications for each subtopic that include supporting arguments for each recommendation and statement.CONCLUSIONS: A consensus conference of experts from around the world developed recommendations and consensus statements for the definition and management of PARDS and identified evidence gaps which need further research.
KW - Acute Lung Injury/diagnosis
KW - Child
KW - Congresses as Topic
KW - Consensus
KW - Critical Care
KW - Humans
KW - Respiratory Distress Syndrome/diagnosis
KW - Systematic Reviews as Topic
KW - consensus development conference
KW - pediatric acute respiratory distress syndrome
KW - pediatric critical care
KW - acute respiratory distress syndrome
KW - evidence-based medicine
UR - http://www.scopus.com/inward/record.url?scp=85146829517&partnerID=8YFLogxK
U2 - 10.1097/PCC.0000000000003160
DO - 10.1097/PCC.0000000000003160
M3 - Review
C2 - 36661437
SN - 1529-7535
VL - 24
SP - S76-S86
JO - Pediatric Critical Care Medicine
JF - Pediatric Critical Care Medicine
IS - 12 Suppl 2
ER -