@article{0f1733367bed4097a423c4bde4b90d28,
title = "Metabolic footprint of Lactobacillus acidophilus NCFM at different pH",
abstract = "Lactobacillus acidophilus NCFM is a well known microorganism from the genomic and probiotic point of view. In order to analyze the potential interactions of NCFM with the surrounding environment, in vitro tests with the metabolic footprinting approach were performed. It was found that NCFM increased the concentration of lactic acid, succinic acid, adenine and arginine in the medium. The metabolism of NCFM did not change significantly between pH 5 and 7, suggesting that other environmental factors than pH might have bigger impact on its colonization throughout the gastrointestinal tract.",
keywords = "GIT, Lactobacillus acidophilus NCFM, LCMS, Metabolite footprint, Metabolomics, Probiotics",
author = "Karolina Sulek and Frandsen, {Henrik Lauritz} and J{\o}rn Smedsgaard and Skov, {Thomas Hjort} and Andrea Wilcks and Licht, {Tine Rask}",
note = "Funding Information: Acknowledgments This work was supported by a grant from the {\O}resund Food (co-financed by The European Union—The European Regional Development Fund and V{\ae}kstforum Hovedstaden; grant no. 09198-02 {\textquoteleft}{\textquoteleft}Bacterial Impact on the Gut Metabolome{\textquoteright}{\textquoteright}) and by the Danish Strategic Research Council{\textquoteright}s Committee on Food and Health (F{\o}su; project no. 2101-06-0067 {\textquoteleft}{\textquoteleft}Biological Production of Dietary Fibres and Prebiotics{\textquoteright}{\textquoteright}). Authors would like to thank Naseer Mahmoud Shukri and Tina Beck Hansen for their contribution to this work as well as Kate Vina Vibefeldt and Bodil Madsen for excellent technical support.",
year = "2012",
month = apr,
doi = "10.1007/s11306-011-0305-4",
language = "English",
volume = "8",
pages = "244--252",
journal = "Metabolomics",
issn = "1573-3882",
publisher = "Springer",
number = "2",
}