Metabolic footprint of Lactobacillus acidophilus NCFM at different pH

Karolina Sulek*, Henrik Lauritz Frandsen, Jørn Smedsgaard, Thomas Hjort Skov, Andrea Wilcks, Tine Rask Licht

*Corresponding author af dette arbejde
12 Citationer (Scopus)

Abstrakt

Lactobacillus acidophilus NCFM is a well known microorganism from the genomic and probiotic point of view. In order to analyze the potential interactions of NCFM with the surrounding environment, in vitro tests with the metabolic footprinting approach were performed. It was found that NCFM increased the concentration of lactic acid, succinic acid, adenine and arginine in the medium. The metabolism of NCFM did not change significantly between pH 5 and 7, suggesting that other environmental factors than pH might have bigger impact on its colonization throughout the gastrointestinal tract.

OriginalsprogEngelsk
TidsskriftMetabolomics
Vol/bind8
Udgave nummer2
Sider (fra-til)244-252
Antal sider9
ISSN1573-3882
DOI
StatusUdgivet - apr. 2012
Udgivet eksterntJa

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