Abstrakt
Messenger RNA transcripts that contain premature stop codons are degraded by a process termed nonsense-mediated mRNA decay (NMD). Although previously thought of as a pathway that rids the cell of non-functional mRNAs arising from mutations and processing errors, new research suggests a more general and evolutionarily important role for NMD in the control of gene expression.
Originalsprog | Engelsk |
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Tidsskrift | Current Biology |
Vol/bind | 15 |
Udgave nummer | 14 |
ISSN | 0960-9822 |
DOI | |
Status | Udgivet - 26 jul. 2005 |