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Mesenchymal stromal cell phenotype is not influenced by confluence during culture expansion

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Haack-Sørensen, Mandana ; Hansen, Susanne Kofoed ; Hansen, Louise ; Gaster, Michael ; Hyttel, Poul ; Ekblond, Annette ; Kastrup, Jens. / Mesenchymal stromal cell phenotype is not influenced by confluence during culture expansion. I: Stem Cell Reviews. 2013 ; Bind 9, Nr. 1. s. 44-58.

Bibtex

@article{6727ae28296c4ac2938e1be8831256f2,
title = "Mesenchymal stromal cell phenotype is not influenced by confluence during culture expansion",
abstract = "Accumulating preclinical and clinical evidence indicates that human mesenchymal stromal cells (MSCs) are good candidates for cell therapy. For clinical applications of MSCs extensive in vitro expansion is required to obtain an adequate number of cells. It is evident that the pursuit for cell quantity must not affect quality, but it is also a fact that in vitro culture conditions affect MSC phenotype. One possible variable is the degree of cell confluence during expansion.",
keywords = "Adult, Biological Markers, Bone Marrow Cells, Cell Count, Cell Culture Techniques, Cell Differentiation, Cell Proliferation, Cells, Cultured, Female, Gene Expression, Humans, Male, Mesenchymal Stromal Cells, Phenotype, RNA, Messenger, Young Adult",
author = "Mandana Haack-S{\o}rensen and Hansen, {Susanne Kofoed} and Louise Hansen and Michael Gaster and Poul Hyttel and Annette Ekblond and Jens Kastrup",
year = "2013",
month = feb,
doi = "10.1007/s12015-012-9386-3",
language = "English",
volume = "9",
pages = "44--58",
journal = "Stem Cell Reviews and Reports",
issn = "1550-8943",
publisher = "Humana Press, Inc",
number = "1",

}

RIS

TY - JOUR

T1 - Mesenchymal stromal cell phenotype is not influenced by confluence during culture expansion

AU - Haack-Sørensen, Mandana

AU - Hansen, Susanne Kofoed

AU - Hansen, Louise

AU - Gaster, Michael

AU - Hyttel, Poul

AU - Ekblond, Annette

AU - Kastrup, Jens

PY - 2013/2

Y1 - 2013/2

N2 - Accumulating preclinical and clinical evidence indicates that human mesenchymal stromal cells (MSCs) are good candidates for cell therapy. For clinical applications of MSCs extensive in vitro expansion is required to obtain an adequate number of cells. It is evident that the pursuit for cell quantity must not affect quality, but it is also a fact that in vitro culture conditions affect MSC phenotype. One possible variable is the degree of cell confluence during expansion.

AB - Accumulating preclinical and clinical evidence indicates that human mesenchymal stromal cells (MSCs) are good candidates for cell therapy. For clinical applications of MSCs extensive in vitro expansion is required to obtain an adequate number of cells. It is evident that the pursuit for cell quantity must not affect quality, but it is also a fact that in vitro culture conditions affect MSC phenotype. One possible variable is the degree of cell confluence during expansion.

KW - Adult

KW - Biological Markers

KW - Bone Marrow Cells

KW - Cell Count

KW - Cell Culture Techniques

KW - Cell Differentiation

KW - Cell Proliferation

KW - Cells, Cultured

KW - Female

KW - Gene Expression

KW - Humans

KW - Male

KW - Mesenchymal Stromal Cells

KW - Phenotype

KW - RNA, Messenger

KW - Young Adult

U2 - 10.1007/s12015-012-9386-3

DO - 10.1007/s12015-012-9386-3

M3 - Journal article

C2 - 22644809

VL - 9

SP - 44

EP - 58

JO - Stem Cell Reviews and Reports

JF - Stem Cell Reviews and Reports

SN - 1550-8943

IS - 1

ER -

ID: 42941469