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Region Hovedstaden - en del af Københavns Universitetshospital
E-pub ahead of print

Membranous septum morphology predicting the risk of conduction abnormalities after transcatheter aortic valve implantation

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

DOI

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  4. Hemodynamic Determinants of Activity Measured by Accelerometer in Patients With Stable Heart Failure

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BACKGROUND: There is limited data on the association of membranous septum (MS) morphology and transcatheter heart valve (THV) implantation depth, and the development of new conduction abnormalities after transcatheter aortic valve replacement (TAVI).

AIMS: To describe the morphology of the MS and predict the risk of new CA after TAVI based on the MS morphology and THV implantation depth.

METHODS: Based on pre-procedural CT-scans the MS depth was measured for every 25% of the entire MS width in 272 TAVI-patients without pre-procedural bundle branch block (BBB) or pacemaker. Post-procedural CT-scans for THV implantation depth assessment were available in 130 of these patients.

RESULTS: The MS depth was a median of 2.5mm (IQR 1.4 - 3.8) deeper at the posterior edge when compared to the anterior edge of the MS. New CA developed in 7.1% of patients in whom the THV did not cross the lower MS border at its anterior edge (3.6% with new BBB and high degree CA, respectively); in 18.8% of patients (15.6% with new BBB and 3.1% with new high-degree CA) where the THV overlapped the lower MS border by <2.5mm and in 47.1% of patients (24.3% with new BBB and 22.9% with new high-degree CA) with THV overlap of the lower MS border by ≥2.5mm.

CONCLUSIONS: The difference of the MS depth and THV implantation depth measured at the anterior edge of the MS predicted new CA after TAVI.

OriginalsprogEngelsk
TidsskriftEuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology
ISSN1774-024X
DOI
StatusE-pub ahead of print - 3 aug. 2021

ID: 68412315