TY - JOUR
T1 - Medication-Related Admissions Among Older Patients in a Danish Emergency Department
T2 - Prevalence, Preventability and Characterisation
AU - Christensen, Louise Westberg Strejby
AU - Dalhoff, Kim Peder
AU - Iversen, Esben
AU - Juul-Larsen, Helle Gybel
AU - Rasmussen, Line Jee Hartmann
AU - Andersen, Aino Leegaard
AU - Andersen, Ove
AU - Houlind, Morten Baltzer
N1 - © 2025 Nordic Association for the Publication of BCPT (former Nordic Pharmacological Society). Published by John Wiley & Sons Ltd.
PY - 2025/12
Y1 - 2025/12
N2 - The prevalence of medication-related admissions (MRAs) among older medical patients admitted to Danish emergency departments (EDs) remains limited. We aimed to determine the prevalence of possibly medication-related admissions (PMRAs) in this population, assess their preventability and identify patient characteristics that distinguish between patients with and without a PMRA. This retrospective, exploratory, descriptive secondary analysis included acutely admitted older medical patients (≥ 65 years) from the ED of Copenhagen University Hospital Hvidovre, Denmark, between October 2018 and April 2021. PMRAs were initially assessed using the Assessment Tool for Hospital Admissions Related to Medications, followed by final classifications and preventability assessments by an experienced panel of pharmacists and a pharmacologist. Among 193 admissions, 31 (16.1%) were classified as PMRAs, and 15 (48.4%) and 11 (35.5%) of these were deemed potentially or definitely preventable, respectively. Untreated conditions (19.4%) and miscommunication (16.1%) were identified as the most common reasons for PMRAs. No specific patient characteristics reliably distinguished between patients with and without a PMRA. In conclusion, MRAs appear to be highly prevalent in Danish EDs, emphasising the need for improved identification and prevention strategies.
AB - The prevalence of medication-related admissions (MRAs) among older medical patients admitted to Danish emergency departments (EDs) remains limited. We aimed to determine the prevalence of possibly medication-related admissions (PMRAs) in this population, assess their preventability and identify patient characteristics that distinguish between patients with and without a PMRA. This retrospective, exploratory, descriptive secondary analysis included acutely admitted older medical patients (≥ 65 years) from the ED of Copenhagen University Hospital Hvidovre, Denmark, between October 2018 and April 2021. PMRAs were initially assessed using the Assessment Tool for Hospital Admissions Related to Medications, followed by final classifications and preventability assessments by an experienced panel of pharmacists and a pharmacologist. Among 193 admissions, 31 (16.1%) were classified as PMRAs, and 15 (48.4%) and 11 (35.5%) of these were deemed potentially or definitely preventable, respectively. Untreated conditions (19.4%) and miscommunication (16.1%) were identified as the most common reasons for PMRAs. No specific patient characteristics reliably distinguished between patients with and without a PMRA. In conclusion, MRAs appear to be highly prevalent in Danish EDs, emphasising the need for improved identification and prevention strategies.
KW - Humans
KW - Denmark/epidemiology
KW - Emergency Service, Hospital/statistics & numerical data
KW - Aged
KW - Male
KW - Female
KW - Aged, 80 and over
KW - Retrospective Studies
KW - Prevalence
KW - Patient Admission/statistics & numerical data
KW - Drug-Related Side Effects and Adverse Reactions/epidemiology
KW - Hospitalization/statistics & numerical data
U2 - 10.1111/bcpt.70132
DO - 10.1111/bcpt.70132
M3 - Journal article
C2 - 41185410
SN - 1742-7843
VL - 137
SP - e70132
JO - Basic & clinical pharmacology & toxicology
JF - Basic & clinical pharmacology & toxicology
IS - 6
M1 - e70132
ER -