Forskning
Udskriv Udskriv
Switch language
Region Hovedstaden - en del af Københavns Universitetshospital
Udgivet

Maternal Serum Resistin Is Reduced in First Trimester Preeclampsia Pregnancies and Is a Marker of Clinical Severity

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. Physical activity during pregnancy and intelligence in sons; A cohort study

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Neurodevelopmental disorder in children believed to have isolated mild ventriculomegaly prenatally

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. New intrauterine shunt for treatment of fetal fluid accumulation: single-center experience of first 17 cases

    Publikation: Bidrag til tidsskriftLetterForskningpeer review

  4. Magnetic Resonance Imaging: A New Tool to Optimize the Prediction of Fetal Anemia?

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Vis graf over relationer

OBJECTIVE: To examine whether resistin levels in first trimester maternal serum are associated with insulin resistance or preeclampsia (PE).

METHODS: A case-control study of maternal serum resistin concentration conducted using 285 normal pregnancies and 123 PE pregnancies matched for gestational age, parity and maternal age. Samples were taken in gestational weeks 10(+0)-13(+6).

RESULTS: There was a negative correlation between resistin and clinical severity of PE, but no correlation with IS, TNF-α, body mass index, birth weight and pregnancy length.

CONCLUSIONS: Resistin is reduced in first trimester of PE pregnancies, particularly in severe PE. Inflammation and IS cannot explain this phenomenon.

OriginalsprogEngelsk
TidsskriftHypertension in Pregnancy
Vol/bind34
Udgave nummer4
Sider (fra-til)422-433
ISSN1064-1955
DOI
StatusUdgivet - 4 dec. 2015

ID: 45855957