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Region Hovedstaden - en del af Københavns Universitetshospital
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Massive fetomaternal hemorrhage caused by an intraplacental choriocarcinoma: a case report

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DOI

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Background. Intraplacental choriocarcinoma is a rare but highly malignant trophoblastic neoplasm. When found near term the risk of maternal metastasis is high because of the late diagnosis. Case. We describe a case of an intraplacental choriocarcinoma diagnosed postpartum after a near-term delivery of a severely anemic infant. A fetomaternal hemorrhage resulted in a hemoglobin concentration in the infant of only 2,1 g/dL. Neither mother nor child showed signs of metastatic disease. The macroscopic examination showed a hydropic placenta weighing more than 1 kilogram. Microscopy showed an intraplacental choriocarcinoma 3 cm in diameter. The tumor had infiltrated the maternal basal plate. Conclusion. Fetomaternal bleeding is a rare form of presentation of choriocarcinoma but its presence should always warrant detailed examination of placenta, mother, and infant.
OriginalsprogEngelsk
TidsskriftCase reports in medicine
Vol/bind2010
Antal sider3
DOI
StatusUdgivet - 1 jan. 2010

ID: 31046092