Mannanbindende lektin og mortalitet hos patienter med type 2-diabetes--sekundaerpublikation

Troels Krarup Hansen, Mari-Anne Gall, Lise Tarnow, Steffen Thiel

3 Citationer (Scopus)

Abstract

We evaluated the relationship between serum mannose-binding lectin (MBL) and mortality and incident albuminuria in 326 patients with type 2 diabetes mellitus (T2DM). During 15 years of follow-up, 169 patients died. In a multivariate analysis, MBL was a significant risk factor for death from any cause and added to the predictive power of CRP. Normoalbuminuric patients with both high MBL and high C-reactive protein (CRP) levels had a significantly increased risk of developing albuminuria. We conclude that MBL alone or in combination with CRP can provide prognostic information on mortality and the development of albuminuria in T2DM

Bidragets oversatte titelMannose-binding lectin and mortality in patients with type 2 diabetes mellitus--secondary publication
OriginalsprogDansk
TidsskriftUgeskrift for Laeger
Vol/bind171
Udgave nummer6
Sider (fra-til)426-9
Antal sider4
ISSN0041-5782
StatusUdgivet - 2 feb. 2009
Udgivet eksterntJa

Emneord

  • Albuminuria
  • C-Reactive Protein
  • Cohort Studies
  • Diabetes Mellitus, Type 2
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Mannose-Binding Lectin
  • Middle Aged
  • Prognosis
  • Proportional Hazards Models
  • Prospective Studies
  • Risk Factors

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