Management of patients with advanced prostate cancer: recommendations of the St Gallen Advanced Prostate Cancer Consensus Conference (APCCC) 2015

S Gillessen; A Omlin; G Attard; J S de Bono; E Efstathiou; K Fizazi; S Halabi; P S Nelson; O Sartor; M R Smith; H R Soule; H Akaza; T M Beer; H Beltran; A M Chinnaiyan; G Daugaard; I D Davis; M De Santis; C G Drake; R A Eeles; S Fanti; M E Gleave; A Heidenreich; M Hussain; N D James; F E Lecouvet; C J Logothetis; K Mastris; S Nilsson; W K Oh; D Olmos; A R Padhani; C Parker; M A Rubin; J A Schalken; H I Scher; A Sella; N D Shore; E J Small; C N Sternberg; H Suzuki; C J Sweeney; I F Tannock; B Tombal

doi:10.1093/annonc/mdv257

Management of patients with advanced prostate cancer: recommendations of the St Gallen Advanced Prostate Cancer Consensus Conference (APCCC) 2015

S Gillessen, A Omlin, G Attard, J S de Bono, E Efstathiou, K Fizazi, S Halabi, P S Nelson, O Sartor, M R Smith, H R Soule, H Akaza, T M Beer, H Beltran, A M Chinnaiyan, G Daugaard, I D Davis, M De Santis, C G Drake, R A EelesS Fanti, M E Gleave, A Heidenreich, M Hussain, N D James, F E Lecouvet, C J Logothetis, K Mastris, S Nilsson, W K Oh, D Olmos, A R Padhani, C Parker, M A Rubin, J A Schalken, H I Scher, A Sella, N D Shore, E J Small, C N Sternberg, H Suzuki, C J Sweeney, I F Tannock, B Tombal

275 Citationer (Scopus)

Abstract

The first St Gallen Advanced Prostate Cancer Consensus Conference (APCCC) Expert Panel identified and reviewed the available evidence for the ten most important areas of controversy in advanced prostate cancer (APC) management. The successful registration of several drugs for castration-resistant prostate cancer and the recent studies of chemo-hormonal therapy in men with castration-naïve prostate cancer have led to considerable uncertainty as to the best treatment choices, sequence of treatment options and appropriate patient selection. Management recommendations based on expert opinion, and not based on a critical review of the available evidence, are presented. The various recommendations carried differing degrees of support, as reflected in the wording of the article text and in the detailed voting results recorded in supplementary Material, available at Annals of Oncology online. Detailed decisions on treatment as always will involve consideration of disease extent and location, prior treatments, host factors, patient preferences as well as logistical and economic constraints. Inclusion of men with APC in clinical trials should be encouraged.

Originalsprog	Engelsk
Tidsskrift	Annals of oncology : official journal of the European Society for Medical Oncology / ESMO
Vol/bind	26
Udgave nummer	8
Sider (fra-til)	1589-604
Antal sider	16
ISSN	0923-7534
DOI	https://doi.org/10.1093/annonc/mdv257
Status	Udgivet - aug. 2015

Adgang til dokumentet

10.1093/annonc/mdv257

Citationsformater

Gillessen, S., Omlin, A., Attard, G., de Bono, J. S., Efstathiou, E., Fizazi, K., Halabi, S., Nelson, P. S., Sartor, O., Smith, M. R., Soule, H. R., Akaza, H., Beer, T. M., Beltran, H., Chinnaiyan, A. M., Daugaard, G., Davis, I. D., De Santis, M., Drake, C. G., ... Tombal, B. (2015). Management of patients with advanced prostate cancer: recommendations of the St Gallen Advanced Prostate Cancer Consensus Conference (APCCC) 2015. Annals of oncology : official journal of the European Society for Medical Oncology / ESMO, 26(8), 1589-604. https://doi.org/10.1093/annonc/mdv257

Management of patients with advanced prostate cancer: recommendations of the St Gallen Advanced Prostate Cancer Consensus Conference (APCCC) 2015. / Gillessen, S; Omlin, A; Attard, G et al.
I: Annals of oncology : official journal of the European Society for Medical Oncology / ESMO, Bind 26, Nr. 8, 08.2015, s. 1589-604.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

Gillessen, S, Omlin, A, Attard, G, de Bono, JS, Efstathiou, E, Fizazi, K, Halabi, S, Nelson, PS, Sartor, O, Smith, MR, Soule, HR, Akaza, H, Beer, TM, Beltran, H, Chinnaiyan, AM, Daugaard, G, Davis, ID, De Santis, M, Drake, CG, Eeles, RA, Fanti, S, Gleave, ME, Heidenreich, A, Hussain, M, James, ND, Lecouvet, FE, Logothetis, CJ, Mastris, K, Nilsson, S, Oh, WK, Olmos, D, Padhani, AR, Parker, C, Rubin, MA, Schalken, JA, Scher, HI, Sella, A, Shore, ND, Small, EJ, Sternberg, CN, Suzuki, H, Sweeney, CJ, Tannock, IF & Tombal, B 2015, 'Management of patients with advanced prostate cancer: recommendations of the St Gallen Advanced Prostate Cancer Consensus Conference (APCCC) 2015', Annals of oncology : official journal of the European Society for Medical Oncology / ESMO, bind 26, nr. 8, s. 1589-604. https://doi.org/10.1093/annonc/mdv257

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title = "Management of patients with advanced prostate cancer: recommendations of the St Gallen Advanced Prostate Cancer Consensus Conference (APCCC) 2015",

abstract = "The first St Gallen Advanced Prostate Cancer Consensus Conference (APCCC) Expert Panel identified and reviewed the available evidence for the ten most important areas of controversy in advanced prostate cancer (APC) management. The successful registration of several drugs for castration-resistant prostate cancer and the recent studies of chemo-hormonal therapy in men with castration-na{\"i}ve prostate cancer have led to considerable uncertainty as to the best treatment choices, sequence of treatment options and appropriate patient selection. Management recommendations based on expert opinion, and not based on a critical review of the available evidence, are presented. The various recommendations carried differing degrees of support, as reflected in the wording of the article text and in the detailed voting results recorded in supplementary Material, available at Annals of Oncology online. Detailed decisions on treatment as always will involve consideration of disease extent and location, prior treatments, host factors, patient preferences as well as logistical and economic constraints. Inclusion of men with APC in clinical trials should be encouraged.",

author = "S Gillessen and A Omlin and G Attard and {de Bono}, {J S} and E Efstathiou and K Fizazi and S Halabi and Nelson, {P S} and O Sartor and Smith, {M R} and Soule, {H R} and H Akaza and Beer, {T M} and H Beltran and Chinnaiyan, {A M} and G Daugaard and Davis, {I D} and {De Santis}, M and Drake, {C G} and Eeles, {R A} and S Fanti and Gleave, {M E} and A Heidenreich and M Hussain and James, {N D} and Lecouvet, {F E} and Logothetis, {C J} and K Mastris and S Nilsson and Oh, {W K} and D Olmos and Padhani, {A R} and C Parker and Rubin, {M A} and Schalken, {J A} and Scher, {H I} and A Sella and Shore, {N D} and Small, {E J} and Sternberg, {C N} and H Suzuki and Sweeney, {C J} and Tannock, {I F} and B Tombal",

note = "{\textcopyright} The Author 2015. Published by Oxford University Press on behalf of the European Society for Medical Oncology.",

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AU - Omlin, A

AU - Attard, G

AU - de Bono, J S

AU - Efstathiou, E

AU - Fizazi, K

AU - Halabi, S

AU - Nelson, P S

AU - Sartor, O

AU - Smith, M R

AU - Soule, H R

AU - Akaza, H

AU - Beer, T M

AU - Beltran, H

AU - Chinnaiyan, A M

AU - Daugaard, G

AU - Davis, I D

AU - De Santis, M

AU - Drake, C G

AU - Eeles, R A

AU - Fanti, S

AU - Gleave, M E

AU - Heidenreich, A

AU - Hussain, M

AU - James, N D

AU - Lecouvet, F E

AU - Logothetis, C J

AU - Mastris, K

AU - Nilsson, S

AU - Oh, W K

AU - Olmos, D

AU - Padhani, A R

AU - Parker, C

AU - Rubin, M A

AU - Schalken, J A

AU - Scher, H I

AU - Sella, A

AU - Shore, N D

AU - Small, E J

AU - Sternberg, C N

AU - Suzuki, H

AU - Sweeney, C J

AU - Tannock, I F

AU - Tombal, B

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N2 - The first St Gallen Advanced Prostate Cancer Consensus Conference (APCCC) Expert Panel identified and reviewed the available evidence for the ten most important areas of controversy in advanced prostate cancer (APC) management. The successful registration of several drugs for castration-resistant prostate cancer and the recent studies of chemo-hormonal therapy in men with castration-naïve prostate cancer have led to considerable uncertainty as to the best treatment choices, sequence of treatment options and appropriate patient selection. Management recommendations based on expert opinion, and not based on a critical review of the available evidence, are presented. The various recommendations carried differing degrees of support, as reflected in the wording of the article text and in the detailed voting results recorded in supplementary Material, available at Annals of Oncology online. Detailed decisions on treatment as always will involve consideration of disease extent and location, prior treatments, host factors, patient preferences as well as logistical and economic constraints. Inclusion of men with APC in clinical trials should be encouraged.

AB - The first St Gallen Advanced Prostate Cancer Consensus Conference (APCCC) Expert Panel identified and reviewed the available evidence for the ten most important areas of controversy in advanced prostate cancer (APC) management. The successful registration of several drugs for castration-resistant prostate cancer and the recent studies of chemo-hormonal therapy in men with castration-naïve prostate cancer have led to considerable uncertainty as to the best treatment choices, sequence of treatment options and appropriate patient selection. Management recommendations based on expert opinion, and not based on a critical review of the available evidence, are presented. The various recommendations carried differing degrees of support, as reflected in the wording of the article text and in the detailed voting results recorded in supplementary Material, available at Annals of Oncology online. Detailed decisions on treatment as always will involve consideration of disease extent and location, prior treatments, host factors, patient preferences as well as logistical and economic constraints. Inclusion of men with APC in clinical trials should be encouraged.

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DO - 10.1093/annonc/mdv257

M3 - Journal article

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SN - 0923-7534

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SP - 1589

EP - 1604

JO - Annals of oncology : official journal of the European Society for Medical Oncology / ESMO

JF - Annals of oncology : official journal of the European Society for Medical Oncology / ESMO

IS - 8

ER -

Management of patients with advanced prostate cancer: recommendations of the St Gallen Advanced Prostate Cancer Consensus Conference (APCCC) 2015

Abstract

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