TY - JOUR
T1 - Low-frequency oscillations and vasoreactivity of cortical vessels in obstructive sleep apnea during wakefulness
T2 - A near infrared spectroscopy study
AU - Schytz, Henrik Winther
AU - Jensen, Benedicte Ersted
AU - Jennum, Poul
AU - Selb, Juliette
AU - Boas, David A
AU - Ashina, Messoud
N1 - Copyright © 2013 Elsevier B.V. All rights reserved.
PY - 2013/5
Y1 - 2013/5
N2 - Effective nasal continuous positive airway pressure (CPAP) therapy reduces the cardiovascular outcomes associated with obstructive sleep apnea (OSA), but the mechanism behind this effect is unclear. We investigated if OSA patients during wakefulness showed signs of increased sympathetic activity and decreased vasoreactivity in cerebral cortical vessels as measured with near-infrared spectroscopy (NIRS), and if this may be reversed by CPAP treatment.
AB - Effective nasal continuous positive airway pressure (CPAP) therapy reduces the cardiovascular outcomes associated with obstructive sleep apnea (OSA), but the mechanism behind this effect is unclear. We investigated if OSA patients during wakefulness showed signs of increased sympathetic activity and decreased vasoreactivity in cerebral cortical vessels as measured with near-infrared spectroscopy (NIRS), and if this may be reversed by CPAP treatment.
U2 - 10.1016/j.sleep.2012.12.009
DO - 10.1016/j.sleep.2012.12.009
M3 - Journal article
C2 - 23517585
SN - 1556-407X
VL - 14
SP - 416
EP - 421
JO - Sleep Medicine Clinics
JF - Sleep Medicine Clinics
IS - 5
ER -