Low-density lipoprotein cholesterol and risk of gallstone disease: A Mendelian randomization study and meta-analyses

Stefan Stender; Ruth Frikke-Schmidt; Marianne Benn; Børge G Nordestgaard; Anne Tybjærg-Hansen

doi:10.1016/j.jhep.2012.08.013

Low-density lipoprotein cholesterol and risk of gallstone disease: A Mendelian randomization study and meta-analyses

Afdeling for Klinisk Biokemi DIA

27 Citationer (Scopus)

Abstract

Drugs which reduce plasma low-density lipoprotein cholesterol (LDL-C) may protect against gallstone disease. Whether plasma levels of LDL-C per se predict risk of gallstone disease remains unclear. We tested the hypothesis that elevated LDL-C is a causal risk factor for symptomatic gallstone disease.

Originalsprog	Engelsk
Tidsskrift	Journal of Hepatology
Vol/bind	58
Udgave nummer	1
Sider (fra-til)	126-33
Antal sider	8
ISSN	0168-8278
DOI	https://doi.org/10.1016/j.jhep.2012.08.013
Status	Udgivet - 2013

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10.1016/j.jhep.2012.08.013

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@article{edecbf6acb4d4e408131df11ec31652d,

title = "Low-density lipoprotein cholesterol and risk of gallstone disease: A Mendelian randomization study and meta-analyses",

abstract = "Drugs which reduce plasma low-density lipoprotein cholesterol (LDL-C) may protect against gallstone disease. Whether plasma levels of LDL-C per se predict risk of gallstone disease remains unclear. We tested the hypothesis that elevated LDL-C is a causal risk factor for symptomatic gallstone disease.",

author = "Stefan Stender and Ruth Frikke-Schmidt and Marianne Benn and Nordestgaard, \{B{\o}rge G\} and Anne Tybj{\ae}rg-Hansen",

year = "2013",

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T1 - Low-density lipoprotein cholesterol and risk of gallstone disease

T2 - A Mendelian randomization study and meta-analyses

AU - Stender, Stefan

AU - Frikke-Schmidt, Ruth

AU - Benn, Marianne

AU - Nordestgaard, Børge G

AU - Tybjærg-Hansen, Anne

PY - 2013

Y1 - 2013

N2 - Drugs which reduce plasma low-density lipoprotein cholesterol (LDL-C) may protect against gallstone disease. Whether plasma levels of LDL-C per se predict risk of gallstone disease remains unclear. We tested the hypothesis that elevated LDL-C is a causal risk factor for symptomatic gallstone disease.

AB - Drugs which reduce plasma low-density lipoprotein cholesterol (LDL-C) may protect against gallstone disease. Whether plasma levels of LDL-C per se predict risk of gallstone disease remains unclear. We tested the hypothesis that elevated LDL-C is a causal risk factor for symptomatic gallstone disease.

U2 - 10.1016/j.jhep.2012.08.013

DO - 10.1016/j.jhep.2012.08.013

M3 - Journal article

C2 - 22922093

SN - 0168-8278

VL - 58

SP - 126

EP - 133

JO - Journal of Hepatology

JF - Journal of Hepatology

IS - 1

ER -

Low-density lipoprotein cholesterol and risk of gallstone disease: A Mendelian randomization study and meta-analyses

Abstract

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