Forskning
Udskriv Udskriv
Switch language
Region Hovedstaden - en del af Københavns Universitetshospital
Udgivet

Long-Term Prognostic Value of Less Stringent Electrocardiographic Q Waves and Fourth Universal Definition of Myocardial Infarction Q Waves

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. Postponement of Death by Pharmacological Heart Failure Treatment: A Meta-Analysis of Randomized Clinical Trials

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Thiazolidinediones and Risk of Atrial Fibrillation Among Patients with Diabetes and Coronary Disease

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Three of a (Peptic) Kind!

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  4. The Reply

    Publikation: Bidrag til tidsskriftKommentar/debatForskningpeer review

  5. Prognostic Impact of Mild Hypokalemia in Terms of Death and Stroke in the General Population-A Prospective Population Study

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. Prevalence and incidence of various Cancer subtypes in patients with heart failure vs matched controls

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Self-reported health status and the associated risk of mortality in heart failure: The DANISH trial

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Fractional Flow Reserve Guided PCI in Patients With and Without Left Ventricular Hypertrophy: a DANAMI-3-PRIMULTI Sub-study

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Vis graf over relationer

BACKGROUND: The Fourth Universal Definition of Myocardial Infarction defines electrocardiographic (ECG) Q waves as duration ≥30ms and amplitude ≥1mm or QS complex in two contiguous leads. However, current taskforce criteria may be overly restrictive. Therefore, we investigated the association of isolated, lenient, or strict Q waves with long-term outcome.

METHODS: From 2001-2015, we included Danish primary care patients with digital ECGs that were evaluated for Q waves. If none occurred, patients had no Q waves. If no other contiguous Q wave occurred, patients had isolated Q waves. If another contiguous Q wave occurred meeting only one criterion (≥30ms and <1mm or <30ms and ≥1mm), patients had lenient Q waves. If another contiguous Q wave occurred, patients had strict Q waves.

RESULTS: Of 365,206 patients, 87,957 had isolated, lenient, or strict Q waves (24%; median age, 61 years; male, 48%), and 277,249 had no Q waves (76%; median age, 53 years; male, 42%). Mortality risk was increased with isolated (all-cause adjusted hazard ratio [aHR], 1.33; 95% confidence interval [CI], 1.29-1.37; cardiovascular-cause aHR, 1.78; 95% CI, 1.70-1.87), lenient (all-cause aHR, 1.41; 95% CI, 1.33-1.50; cardiovascular-cause aHR, 1.78; 95% CI, 1.63-1.94), or strict (all-cause aHR, 1.64; 95% CI, 1.57-1.72; cardiovascular-cause aHR, 2.70; 95% CI, 2.52-2.89) Q waves compared with no Q waves. Highest mortality risk was associated with anteroseptal lenient or strict Q waves.

CONCLUSIONS: This large contemporary analysis suggests that less stringent Q-wave criteria carry prognostic value in predicting adverse outcome among primary care patients.

OriginalsprogEngelsk
TidsskriftAmerican Journal of Medicine
Vol/bind133
Udgave nummer5
Sider (fra-til)582-589.e7
ISSN0002-9343
DOI
StatusUdgivet - maj 2020

ID: 58253218