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Region Hovedstaden - en del af Københavns Universitetshospital
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Long-term impact of incisional hernia on quality of life after colonic cancer resection

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

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PURPOSE: The objective of the current study was to examine the long-term quality of life (QOL) after colonic cancer resection according to whether or not the patients developed incisional hernia. Furthermore, the impact of incisional hernia repair on QOL was examined in the patient group diagnosed with an incisional hernia.

METHODS: This was a nationwide register-based study including patients undergoing colonic cancer resection identified in the Danish Colorectal Cancer Group database. Surviving patients were contacted and answered the EORTC QLQ-C30 questionnaire and grouped according to subsequent incisional hernia diagnosis, and in a subgroup analysis of patients with subsequent incisional hernia according to incisional hernia repair or not.

RESULTS: A total of 2466 patients were included. The median time from colonic cancer resection to QOL assessment was 9.9 years, during which a total of 215 (8.7%) patients were diagnosed with incisional hernia, and 156 (72.6%) of these underwent incisional hernia repair. After adjustment for confounders, incisional hernia subsequent to colonic cancer resection was significantly associated with reduced QOL in the domains Global health, Physical functioning, Role functioning, Emotional functioning and Social functioning, as well as significantly associated with increased symptoms in the scales of pain, dyspnoea and insomnia. Of patients with incisional hernia, surgical repair was associated with increased QOL in the domains Physical functioning and Role functioning.

CONCLUSIONS: Incisional hernia subsequent to colonic cancer resection was associated with reduced QOL several years after surgery and should be considered taken into account when evaluating the long-term outcome of colonic cancer resection.

OriginalsprogEngelsk
TidsskriftHernia : the journal of hernias and abdominal wall surgery
Vol/bind24
Udgave nummer2
Sider (fra-til)265-272
Antal sider8
ISSN1265-4906
DOI
StatusUdgivet - apr. 2020

ID: 61703198