Long-term treatment effect of trauma-affected refugees with flexible cognitive behavioural therapy and antidepressants

Caecilie Böck Buhmann, Merete Nordentoft, Morten Ekstroem, Jessica Carlsson, Erik Lykke Mortensen

13 Citationer (Scopus)

Abstract

Few studies exist on the long-term effect of treatment of trauma-affected refugees. The purpose of this study was to estimate the long-term treatment effects of cognitive behavioural therapy and antidepressants (sertraline and
mianserin) in trauma-affected refugees. Follow-ups were conducted 6 and 18 months after a randomised controlled clinical trial. The included patients were refugees with war-related traumatic experiences, PTSD and without psychotic disorders. We found a small improvement over time in PTSD, depression and anxiety symptoms and level of functioning, but the improvement was not associated with any specific treatment. Personality change after catastrophic experiences and life events influenced the symptom level at all follow-ups
while depression at completion of treatment was associated with a steeper decline in symptom load at the followups. In spite of the limited decline in symptom scores and treatment effects immediately after treatment, the
condition of the treated trauma-affected refugees was significantly improved 6 and 18 months after treatment although the improvement was small.
OriginalsprogEngelsk
TidsskriftPsychiatry Research
Vol/bind264
Sider (fra-til)217-223
Antal sider7
ISSN0165-1781
DOI
StatusUdgivet - jun. 2018

Emneord

  • Sundhedsvidenskab
  • Transcultural Psychiatry
  • Psychotherapy
  • Randomized Controlled Trial
  • Pharmacology

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