Long-term effects of growth hormone (GH) on body fluid distribution in GH deficient adults: a four months double blind placebo controlled trial

Sidse Fisker; A M Rosenfalck; E Frandsen; J O Jørgensen; J Hilsted; J S Christiansen

Long-term effects of growth hormone (GH) on body fluid distribution in GH deficient adults: a four months double blind placebo controlled trial

Sidse Fisker, A M Rosenfalck, E Frandsen, J O Jørgensen, J Hilsted, J S Christiansen

19 Citationer (Scopus)

Abstrakt

Short-term growth hormone (GH) treatment normalises body fluid distribution in adult GH deficient patients, but the impact of long-term treatment on body fluid homeostasis has hitherto not been thoroughly examined in placebo controlled trials. To investigate if the water retaining effect of GH persists for a longer time we examined the impact of 4 months GH treatment on extracellular volume (ECV) and plasma volume (PV) in GH deficient adults.

Originalsprog	Engelsk
Tidsskrift	European journal of endocrinology / European Federation of Endocrine Societies
Vol/bind	140
Udgave nummer	1
Sider (fra-til)	11-6
Antal sider	6
ISSN	0804-4643
Status	Udgivet - jan. 1999
Udgivet eksternt	Ja

Citationsformater

Long-term effects of growth hormone (GH) on body fluid distribution in GH deficient adults : a four months double blind placebo controlled trial. / Fisker, Sidse; Rosenfalck, A M; Frandsen, E et al.

I: European journal of endocrinology / European Federation of Endocrine Societies, Bind 140, Nr. 1, 01.1999, s. 11-6.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

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title = "Long-term effects of growth hormone (GH) on body fluid distribution in GH deficient adults: a four months double blind placebo controlled trial",

abstract = "Short-term growth hormone (GH) treatment normalises body fluid distribution in adult GH deficient patients, but the impact of long-term treatment on body fluid homeostasis has hitherto not been thoroughly examined in placebo controlled trials. To investigate if the water retaining effect of GH persists for a longer time we examined the impact of 4 months GH treatment on extracellular volume (ECV) and plasma volume (PV) in GH deficient adults.",

keywords = "Adult, Blood Pressure, Body Composition, Body Fluids, Double-Blind Method, Extracellular Space, Female, Growth Hormone, Homeostasis, Human Growth Hormone, Humans, Insulin-Like Growth Factor I, Male, Middle Aged, Plasma Volume, Renin",

author = "Sidse Fisker and Rosenfalck, {A M} and E Frandsen and J{\o}rgensen, {J O} and J Hilsted and Christiansen, {J S}",

year = "1999",

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language = "English",

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T1 - Long-term effects of growth hormone (GH) on body fluid distribution in GH deficient adults

T2 - a four months double blind placebo controlled trial

AU - Fisker, Sidse

AU - Rosenfalck, A M

AU - Frandsen, E

AU - Jørgensen, J O

AU - Hilsted, J

AU - Christiansen, J S

PY - 1999/1

Y1 - 1999/1

N2 - Short-term growth hormone (GH) treatment normalises body fluid distribution in adult GH deficient patients, but the impact of long-term treatment on body fluid homeostasis has hitherto not been thoroughly examined in placebo controlled trials. To investigate if the water retaining effect of GH persists for a longer time we examined the impact of 4 months GH treatment on extracellular volume (ECV) and plasma volume (PV) in GH deficient adults.

AB - Short-term growth hormone (GH) treatment normalises body fluid distribution in adult GH deficient patients, but the impact of long-term treatment on body fluid homeostasis has hitherto not been thoroughly examined in placebo controlled trials. To investigate if the water retaining effect of GH persists for a longer time we examined the impact of 4 months GH treatment on extracellular volume (ECV) and plasma volume (PV) in GH deficient adults.

KW - Adult

KW - Blood Pressure

KW - Body Composition

KW - Body Fluids

KW - Double-Blind Method

KW - Extracellular Space

KW - Female

KW - Growth Hormone

KW - Homeostasis

KW - Human Growth Hormone

KW - Humans

KW - Insulin-Like Growth Factor I

KW - Male

KW - Middle Aged

KW - Plasma Volume

KW - Renin

M3 - Journal article

C2 - 10037245

VL - 140

SP - 11

EP - 16

JO - European Journal of Endocrinology

JF - European Journal of Endocrinology

SN - 0804-4643

IS - 1

ER -

Long-term effects of growth hormone (GH) on body fluid distribution in GH deficient adults: a four months double blind placebo controlled trial

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