TY - JOUR
T1 - Long-term effects of attention deficit hyperactivity disorder (ADHD) on social functioning and health care outcomes
AU - Jennum, Poul
AU - Sørensen, Anne Virring
AU - Baandrup, Lone
AU - Ibsen, Michael
AU - Ibsen, Rikke
AU - Kjellberg, Jakob
N1 - Copyright © 2025 Elsevier Ltd. All rights reserved.
PY - 2025/2
Y1 - 2025/2
N2 - INTRODUCTION: Research on the long-term effects of treatment for attention deficit hyperactivity disorder (ADHD) on educational and social outcomes is limited. This study aims to evaluate long-term social functioning outcomes in patients with ADHD and the potential effects of pharmacological treatment for ADHD.METHODS: We used National Patient Registry data from 1995 to 2016 to identify patients diagnosed with ADHD and those collecting ADHD medication. Eligible patients were under 30 years old or had reached 30 between 2005 and 2016, ensuring a minimum 10-year observation period. A case-control design was applied, matching ADHD patients in a ratio of 1:4 with the general population based on age, sex, and residential municipality at the index year.RESULTS: Patients with ADHD experienced substantial socioeconomic difficulties, indicated by increased direct health care costs, higher rates of psychiatric comorbidities, and greater co-medication use compared with controls. No association was found between adherence to ADHD medication and completion of education at age 30 years. Adherence to ADHD medication appeared to negatively impact employment status at age 30, confounded by the severity of psychiatric comorbidity.CONCLUSIONS: Despite available treatments, patients with ADHD lag in achieving social functioning outcomes. Further research is needed to better understand how to support patients with ADHD in order to close the gaps in health and socioeconomic status.
AB - INTRODUCTION: Research on the long-term effects of treatment for attention deficit hyperactivity disorder (ADHD) on educational and social outcomes is limited. This study aims to evaluate long-term social functioning outcomes in patients with ADHD and the potential effects of pharmacological treatment for ADHD.METHODS: We used National Patient Registry data from 1995 to 2016 to identify patients diagnosed with ADHD and those collecting ADHD medication. Eligible patients were under 30 years old or had reached 30 between 2005 and 2016, ensuring a minimum 10-year observation period. A case-control design was applied, matching ADHD patients in a ratio of 1:4 with the general population based on age, sex, and residential municipality at the index year.RESULTS: Patients with ADHD experienced substantial socioeconomic difficulties, indicated by increased direct health care costs, higher rates of psychiatric comorbidities, and greater co-medication use compared with controls. No association was found between adherence to ADHD medication and completion of education at age 30 years. Adherence to ADHD medication appeared to negatively impact employment status at age 30, confounded by the severity of psychiatric comorbidity.CONCLUSIONS: Despite available treatments, patients with ADHD lag in achieving social functioning outcomes. Further research is needed to better understand how to support patients with ADHD in order to close the gaps in health and socioeconomic status.
KW - Attention deficit hyperactivity disorder
KW - Education
KW - Employment
KW - Health care costs
KW - Psychiatric comorbidity
UR - http://www.scopus.com/inward/record.url?scp=85214840830&partnerID=8YFLogxK
U2 - 10.1016/j.jpsychires.2025.01.016
DO - 10.1016/j.jpsychires.2025.01.016
M3 - Journal article
C2 - 39818109
SN - 0022-3956
VL - 182
SP - 212
EP - 220
JO - Journal of Psychiatric Research
JF - Journal of Psychiatric Research
ER -