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Long-term benefits and risks of drug-eluting compared to bare-metal stents in patients with versus without chronic kidney disease

  • Maria Wanitschek
  • , Matthias Pfisterer
  • , Anders Hvelplund
  • , Stefano De Servi
  • , Osmund Bertel
  • , Raban Jeger
  • , Peter Rickenbacher
  • , Allan Iversen
  • , Jan Skov Jensen
  • , Soeren Galatius
  • , Christoph Kaiser
  • , Hannes Alber
  • , BASKET-PROVE Investigators
    15 Citationer (Scopus)

    Abstract

    AIMS: Chronic kidney disease (CKD) is associated with worse outcomes in patients with coronary artery disease (CAD). How CKD influences the benefit-risk balance of drug-eluting stents (DES) versus bare-metal stents (BMS) is less known. METHODS AND RESULTS: In the multicentre BASKET-PROVE trial, 2314 patients in need of large coronary stenting (≥3.0mm) were randomised 2:1 to DES or BMS. In an a priori planned secondary analysis, outcomes were evaluated according to renal function defined by estimated glomerular filtration rates (eGFR; normal: eGFR≥60ml/min/1.73m(2); CKD: eGFR
    OriginalsprogEngelsk
    TidsskriftInternational Journal of Cardiology Research
    Vol/bind20
    Udgave nummer6
    Sider (fra-til)2381-8
    DOI
    StatusUdgivet - 3 okt. 2013

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