Long-term benefits and risks of drug-eluting compared to bare-metal stents in patients with versus without chronic kidney disease

Maria Wanitschek, Matthias Pfisterer, Anders Hvelplund, Stefano De Servi, Osmund Bertel, Raban Jeger, Peter Rickenbacher, Allan Iversen, Jan Skov Jensen, Soeren Galatius, Christoph Kaiser, Hannes Alber, for the BASKET-PROVE Investigators

    15 Citationer (Scopus)

    Abstract

    AIMS: Chronic kidney disease (CKD) is associated with worse outcomes in patients with coronary artery disease (CAD). How CKD influences the benefit-risk balance of drug-eluting stents (DES) versus bare-metal stents (BMS) is less known. METHODS AND RESULTS: In the multicentre BASKET-PROVE trial, 2314 patients in need of large coronary stenting (≥3.0mm) were randomised 2:1 to DES or BMS. In an a priori planned secondary analysis, outcomes were evaluated according to renal function defined by estimated glomerular filtration rates (eGFR; normal: eGFR≥60ml/min/1.73m(2); CKD: eGFR
    OriginalsprogEngelsk
    TidsskriftInternational Journal of Cardiology Research
    Vol/bind20
    Udgave nummer6
    Sider (fra-til)2381-8
    DOI
    StatusUdgivet - 3 okt. 2013

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