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Region Hovedstaden - en del af Københavns Universitetshospital
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Liver pathology associated with the use of anabolic-androgenic steroids

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

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  • Katrine Søe
  • Martin Jensen Søe
  • C Gluud
Vis graf over relationer
This review examines the liver-damaging side effects of anabolic-androgenic steroids (AAS). It seems that AAS can cause development of peliosis hepatis, subcellular changes of hepatocytes, hepatocellular hyperplasia and hepatocellular adenomas. On the other hand, it has not been convincingly proved that AAS can cause development of hepatocellular carcinomas when used in the usual therapeutic doses. Tumours reported as hepatocellular carcinomas caused by AAS seems to be hyperplastic lesions of a benign nature able to regress with withdrawal of the putative agent. The effects of untraditional combinations and high-dose AAS are not yet known, leaving the possibility of a carcinogenic effect in those cases.
OriginalsprogEngelsk
TidsskriftLiver
Vol/bind12
Udgave nummer2
Sider (fra-til)73-9
Antal sider7
ISSN0106-9543
StatusUdgivet - apr. 1992

ID: 38931757