Liver function during chronic renal failure in rabbits

E Tvedegaard; H E Poulsen; H Vilstrup; H K Thomsen

doi:10.1007/BF01946660

Liver function during chronic renal failure in rabbits

E Tvedegaard, H E Poulsen, H Vilstrup, H K Thomsen

Abstract

In rabbits with chronic renal insufficiency the prothrombin index was increased by 25% and the alanine aminotransferase activity decreased by 20%; the results of other routine tests of hepatic function were not affected. The galactose elimination capacity was decreased by 12%, whereas the body clearance of antipyrine was unchanged. No change in hepatocytic structure was found.

Originalsprog	Engelsk
Tidsskrift	Experientia
Vol/bind	40
Udgave nummer	11
Sider (fra-til)	1255-6
Antal sider	2
ISSN	0014-4754
DOI	https://doi.org/10.1007/BF01946660
Status	Udgivet - 15 nov. 1984

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10.1007/BF01946660

Citationsformater

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title = "Liver function during chronic renal failure in rabbits",

abstract = "In rabbits with chronic renal insufficiency the prothrombin index was increased by 25% and the alanine aminotransferase activity decreased by 20%; the results of other routine tests of hepatic function were not affected. The galactose elimination capacity was decreased by 12%, whereas the body clearance of antipyrine was unchanged. No change in hepatocytic structure was found.",

keywords = "Alanine Transaminase/metabolism, Alkaline Phosphatase/metabolism, Animals, Galactose/metabolism, Kidney Failure, Chronic/pathology, Liver/pathology, Male, Prothrombin Time, Rabbits",

author = "E Tvedegaard and Poulsen, {H E} and H Vilstrup and Thomsen, {H K}",

year = "1984",

month = nov,

day = "15",

doi = "10.1007/BF01946660",

language = "English",

volume = "40",

pages = "1255--6",

journal = "Experientia",

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TY - JOUR

T1 - Liver function during chronic renal failure in rabbits

AU - Tvedegaard, E

AU - Poulsen, H E

AU - Vilstrup, H

AU - Thomsen, H K

PY - 1984/11/15

Y1 - 1984/11/15

N2 - In rabbits with chronic renal insufficiency the prothrombin index was increased by 25% and the alanine aminotransferase activity decreased by 20%; the results of other routine tests of hepatic function were not affected. The galactose elimination capacity was decreased by 12%, whereas the body clearance of antipyrine was unchanged. No change in hepatocytic structure was found.

AB - In rabbits with chronic renal insufficiency the prothrombin index was increased by 25% and the alanine aminotransferase activity decreased by 20%; the results of other routine tests of hepatic function were not affected. The galactose elimination capacity was decreased by 12%, whereas the body clearance of antipyrine was unchanged. No change in hepatocytic structure was found.

KW - Alanine Transaminase/metabolism

KW - Alkaline Phosphatase/metabolism

KW - Animals

KW - Galactose/metabolism

KW - Kidney Failure, Chronic/pathology

KW - Liver/pathology

KW - Male

KW - Prothrombin Time

KW - Rabbits

U2 - 10.1007/BF01946660

DO - 10.1007/BF01946660

M3 - Journal article

C2 - 6500010

SN - 0014-4754

VL - 40

SP - 1255

EP - 1256

JO - Experientia

JF - Experientia

IS - 11

ER -

Liver function during chronic renal failure in rabbits

Abstract

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