Life-long endurance exercise in humans: Circulating levels of inflammatory markers and leg muscle size

U R Mikkelsen; C Couppé; A Karlsen; J F Grosset; P Schjerling; A L Mackey; H H Klausen; S P Magnusson; M Kjær

doi:10.1016/j.mad.2013.11.004

Life-long endurance exercise in humans: Circulating levels of inflammatory markers and leg muscle size

U R Mikkelsen, C Couppé, A Karlsen, J F Grosset, P Schjerling, A L Mackey, H H Klausen, S P Magnusson, M Kjær

97 Citationer (Scopus)

Abstract

Human aging is associated with a loss of skeletal muscle and an increase in circulating inflammatory markers. It is unknown whether endurance training (Tr) can prevent these changes. Therefore we studied 15 old trained (O-Tr) healthy males and, for comparison, 12 old untrained (O-Un), 10 Young-Tr (Y-Tr) and 12 Young-Un (Y-Un). Quadriceps size, VO2 peak, CRP, IL-6, TNF-α and its receptors, suPAR, lipid profile, leucocytes and glucose homeostasis were measured. Tr was associated with an improved insulin profile (p

Originalsprog	Engelsk
Tidsskrift	Mechanisms of Ageing and Development
Vol/bind	134
Udgave nummer	11-12
Sider (fra-til)	531-40
Antal sider	10
ISSN	0047-6374
DOI	https://doi.org/10.1016/j.mad.2013.11.004
Status	Udgivet - 2013

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10.1016/j.mad.2013.11.004

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title = "Life-long endurance exercise in humans: Circulating levels of inflammatory markers and leg muscle size",

abstract = "Human aging is associated with a loss of skeletal muscle and an increase in circulating inflammatory markers. It is unknown whether endurance training (Tr) can prevent these changes. Therefore we studied 15 old trained (O-Tr) healthy males and, for comparison, 12 old untrained (O-Un), 10 Young-Tr (Y-Tr) and 12 Young-Un (Y-Un). Quadriceps size, VO2 peak, CRP, IL-6, TNF-α and its receptors, suPAR, lipid profile, leucocytes and glucose homeostasis were measured. Tr was associated with an improved insulin profile (p",

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T2 - Circulating levels of inflammatory markers and leg muscle size

AU - Mikkelsen, U R

AU - Couppé, C

AU - Karlsen, A

AU - Grosset, J F

AU - Schjerling, P

AU - Mackey, A L

AU - Klausen, H H

AU - Magnusson, S P

AU - Kjær, M

PY - 2013

Y1 - 2013

N2 - Human aging is associated with a loss of skeletal muscle and an increase in circulating inflammatory markers. It is unknown whether endurance training (Tr) can prevent these changes. Therefore we studied 15 old trained (O-Tr) healthy males and, for comparison, 12 old untrained (O-Un), 10 Young-Tr (Y-Tr) and 12 Young-Un (Y-Un). Quadriceps size, VO2 peak, CRP, IL-6, TNF-α and its receptors, suPAR, lipid profile, leucocytes and glucose homeostasis were measured. Tr was associated with an improved insulin profile (p

AB - Human aging is associated with a loss of skeletal muscle and an increase in circulating inflammatory markers. It is unknown whether endurance training (Tr) can prevent these changes. Therefore we studied 15 old trained (O-Tr) healthy males and, for comparison, 12 old untrained (O-Un), 10 Young-Tr (Y-Tr) and 12 Young-Un (Y-Un). Quadriceps size, VO2 peak, CRP, IL-6, TNF-α and its receptors, suPAR, lipid profile, leucocytes and glucose homeostasis were measured. Tr was associated with an improved insulin profile (p

UR - https://www.scopus.com/pages/publications/84891560151

U2 - 10.1016/j.mad.2013.11.004

DO - 10.1016/j.mad.2013.11.004

M3 - Journal article

C2 - 24287006

SN - 0047-6374

VL - 134

SP - 531

EP - 540

JO - Mechanisms of Ageing and Development

JF - Mechanisms of Ageing and Development

IS - 11-12

ER -

Life-long endurance exercise in humans: Circulating levels of inflammatory markers and leg muscle size

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