Life-long endurance exercise in humans: Circulating levels of inflammatory markers and leg muscle size

U R Mikkelsen, C Couppé, A Karlsen, J F Grosset, P Schjerling, A L Mackey, H H Klausen, S P Magnusson, M Kjær

95 Citationer (Scopus)

Abstract

Human aging is associated with a loss of skeletal muscle and an increase in circulating inflammatory markers. It is unknown whether endurance training (Tr) can prevent these changes. Therefore we studied 15 old trained (O-Tr) healthy males and, for comparison, 12 old untrained (O-Un), 10 Young-Tr (Y-Tr) and 12 Young-Un (Y-Un). Quadriceps size, VO2 peak, CRP, IL-6, TNF-α and its receptors, suPAR, lipid profile, leucocytes and glucose homeostasis were measured. Tr was associated with an improved insulin profile (p
OriginalsprogEngelsk
TidsskriftMechanisms of Ageing and Development
Vol/bind134
Udgave nummer11-12
Sider (fra-til)531-40
Antal sider10
ISSN0047-6374
DOI
StatusUdgivet - 2013

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