TY - JOUR
T1 - LibHip
T2 - An open-access hip joint model repository suitable for finite element method simulation
AU - Moshfeghifar, Faezeh
AU - Gholamalizadeh, Torkan
AU - Ferguson, Zachary
AU - Schneider, Teseo
AU - Nielsen, Michael Bachmann
AU - Panozzo, Daniele
AU - Darkner, Sune
AU - Erleben, Kenny
N1 - Copyright © 2022 The Author(s). Published by Elsevier B.V. All rights reserved.
PY - 2022/11
Y1 - 2022/11
N2 - BACKGROUND AND OBJECTIVE: population-based finite element analysis of hip joints allows us to understand the effect of inter-subject variability on simulation results. Developing large subject-specific population models is challenging and requires extensive manual effort. Thus, the anatomical representations are often subjected to simplification. The discretized geometries do not guarantee conformity in shared interfaces, leading to complications in setting up simulations. Additionally, these models are not openly accessible, challenging reproducibility. Our work provides multiple subject-specific hip joint finite element models and a novel semi-automated modeling workflow.METHODS: we reconstruct 11 healthy subject-specific models, including the sacrum, the paired pelvic bones, the paired proximal femurs, the paired hip joints, the paired sacroiliac joints, and the pubic symphysis. The bones are derived from CT scans, and the cartilages are generated from the bone geometries. We generate the whole complex's volume mesh with conforming interfaces. Our models are evaluated using both mesh quality metrics and simulation experiments.RESULTS: the geometry of all the models are inspected by our clinical expert and show high-quality discretization with accurate geometries. The simulations produce smooth stress patterns, and the variance among the subjects highlights the effect of inter-subject variability and asymmetry in the predicted results.CONCLUSIONS: our work is one of the largest model repositories with respect to the number of subjects and regions of interest in the hip joint area. Our detailed research data, including the clinical images, the segmentation label maps, the finite element models, and software tools, are openly accessible on GitHub and the link is provided in Moshfeghifar et al.(2022)[1]. Our aim is to empower clinical researchers to have free access to verified and reproducible models. In future work, we aim to add additional structures to our models.
AB - BACKGROUND AND OBJECTIVE: population-based finite element analysis of hip joints allows us to understand the effect of inter-subject variability on simulation results. Developing large subject-specific population models is challenging and requires extensive manual effort. Thus, the anatomical representations are often subjected to simplification. The discretized geometries do not guarantee conformity in shared interfaces, leading to complications in setting up simulations. Additionally, these models are not openly accessible, challenging reproducibility. Our work provides multiple subject-specific hip joint finite element models and a novel semi-automated modeling workflow.METHODS: we reconstruct 11 healthy subject-specific models, including the sacrum, the paired pelvic bones, the paired proximal femurs, the paired hip joints, the paired sacroiliac joints, and the pubic symphysis. The bones are derived from CT scans, and the cartilages are generated from the bone geometries. We generate the whole complex's volume mesh with conforming interfaces. Our models are evaluated using both mesh quality metrics and simulation experiments.RESULTS: the geometry of all the models are inspected by our clinical expert and show high-quality discretization with accurate geometries. The simulations produce smooth stress patterns, and the variance among the subjects highlights the effect of inter-subject variability and asymmetry in the predicted results.CONCLUSIONS: our work is one of the largest model repositories with respect to the number of subjects and regions of interest in the hip joint area. Our detailed research data, including the clinical images, the segmentation label maps, the finite element models, and software tools, are openly accessible on GitHub and the link is provided in Moshfeghifar et al.(2022)[1]. Our aim is to empower clinical researchers to have free access to verified and reproducible models. In future work, we aim to add additional structures to our models.
KW - Humans
KW - Finite Element Analysis
KW - Reproducibility of Results
KW - Hip Joint/diagnostic imaging
KW - Computer Simulation
KW - Pelvis/diagnostic imaging
KW - Biomechanical Phenomena
UR - http://www.scopus.com/inward/record.url?scp=85138402570&partnerID=8YFLogxK
U2 - 10.1016/j.cmpb.2022.107140
DO - 10.1016/j.cmpb.2022.107140
M3 - Journal article
C2 - 36162245
SN - 0169-2607
VL - 226
JO - Computer Methods and Programs in Biomedicine
JF - Computer Methods and Programs in Biomedicine
M1 - 107140
ER -