Leverresektioner gennem ti år

AIMS: The results after liver resection have improved over the last decade with an operative mortality rate of less than 5% in high-volume centres. The aim of the present study was to assess the perioperative outcome after hepatic resection and to assess the long-term survival after liver resection of hepatic metastases from colorectal cancer and hepatocellular carcinoma in our institution.

MATERIALS AND METHODS: The patients who underwent their primary liver resection from 1.1.1995-31.12.2004 in our institution were included. The surgical outcome was reviewed retrospectively and the five-year survival after resection of hepatic metastases from colorectal cancer and hepatocellular carcinoma was estimated.

RESULTS: 141 patients (71M/70F), median age 58 years (1-78), underwent a liver resection in the ten-year period. The number of resections increased from two in 1995 to 32 in 2004. Median hospital stay was 9 days (3-38). The most frequent complication was biliary leakage (7.8%), haemorrhage (2.8%) and hepatic insufficiency (2.8%). 30-days mortality was 1.4%. The actuarial 5-survival after hepatic resection for colorectal liver metastases and hepatocellular carcinoma was 39% and 42%, respectively.

CONCLUSION: The morbidity and mortality rate after hepatic resection and the long-term survival for patients undergoing resection for hepatic metastases from colorectal cancer and hepatocellular carcinoma in our institution are comparable with the best high-volume centres.