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Region Hovedstaden - en del af Københavns Universitetshospital
Udgivet

Level of Notch activation determines the effect on growth and stem cell-like features in glioblastoma multiforme neurosphere cultures

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

DOI

  1. Identification of Tumor Antigens Among the HLA Peptidomes of Glioblastoma Tumors and Plasma

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Withdrawal: Identification of tumor antigens among the HLA peptidomes of glioblastoma tumors and plasma

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Actively personalized vaccination trial for newly diagnosed glioblastoma

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  4. Extracranial metastases in glioblastoma-Two case stories

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  5. Feasibility of multi-parametric PET and MRI for prediction of tumour recurrence in patients with glioblastoma

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Vis graf over relationer
Brain cancer stem-like cells (bCSC) are cancer cells with neural stem cell (NSC)-like properties found in glioblastoma multiforme (GBM) and they are assigned a central role in tumor initiation, progression and relapse. The Notch pathway is important for maintenance and cell fate decisions in the normal NSC population. Notch signaling is often deregulated in GBM and recent results suggest that this pathway plays a significant role in bCSC as well. We therefore wished to further elucidate the role of Notch activation in GBM-derived bCSC.
OriginalsprogEngelsk
TidsskriftCancer Biology & Therapy
Vol/bind14
Udgave nummer7
Sider (fra-til)625-37
Antal sider13
ISSN1538-4047
DOI
StatusUdgivet - jul. 2013

ID: 42485188