Level of complement activity predicts cardiac dysfunction after acute myocardial infarction treated with primary percutaneous coronary intervention

Sune Haahr-Pedersen; Mette Bjerre; Allan Flyvbjerg; Rasmus Mogelvang; Helena Dominquez; Troels Krarup Hansen; Søren Galatius; Jan Bech; Jan Kyst Madsen; Peter Søgaard; Jan Skov Jensen

Level of complement activity predicts cardiac dysfunction after acute myocardial infarction treated with primary percutaneous coronary intervention

Sune Haahr-Pedersen, Mette Bjerre, Allan Flyvbjerg, Rasmus Mogelvang, Helena Dominquez, Troels Krarup Hansen, Søren Galatius, Jan Bech, Jan Kyst Madsen, Peter Søgaard, Jan Skov Jensen

33 Citationer (Scopus)

Abstract

The positive effect of reperfusion after ST-elevation myocardial infarction (STEMI) can be reduced by ischemic/reperfusion (I/R) injury.Mannose-binding-lectin (MBL) and soluble C5b-9 (membrane-attack-complex) are involved in complement-driven cell lysis and may play a role in human myocardial I/R injury. We evaluated the potential association between MBL and sC5b-9 in plasma and subsequent cardiac dysfunction in patients with STEMI treated with primary percutaneous coronary intervention (pPCI).

Originalsprog	Engelsk
Tidsskrift	The Journal of invasive cardiology
Vol/bind	21
Udgave nummer	1
Sider (fra-til)	13-9
Antal sider	7
Status	Udgivet - 1 jan. 2009

Citationsformater

Level of complement activity predicts cardiac dysfunction after acute myocardial infarction treated with primary percutaneous coronary intervention. / Haahr-Pedersen, Sune; Bjerre, Mette; Flyvbjerg, Allan et al.
I: The Journal of invasive cardiology, Bind 21, Nr. 1, 01.01.2009, s. 13-9.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

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abstract = "The positive effect of reperfusion after ST-elevation myocardial infarction (STEMI) can be reduced by ischemic/reperfusion (I/R) injury.Mannose-binding-lectin (MBL) and soluble C5b-9 (membrane-attack-complex) are involved in complement-driven cell lysis and may play a role in human myocardial I/R injury. We evaluated the potential association between MBL and sC5b-9 in plasma and subsequent cardiac dysfunction in patients with STEMI treated with primary percutaneous coronary intervention (pPCI).",

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AU - Haahr-Pedersen, Sune

AU - Bjerre, Mette

AU - Flyvbjerg, Allan

AU - Mogelvang, Rasmus

AU - Dominquez, Helena

AU - Hansen, Troels Krarup

AU - Galatius, Søren

AU - Bech, Jan

AU - Madsen, Jan Kyst

AU - Søgaard, Peter

AU - Jensen, Jan Skov

PY - 2009/1/1

Y1 - 2009/1/1

N2 - The positive effect of reperfusion after ST-elevation myocardial infarction (STEMI) can be reduced by ischemic/reperfusion (I/R) injury.Mannose-binding-lectin (MBL) and soluble C5b-9 (membrane-attack-complex) are involved in complement-driven cell lysis and may play a role in human myocardial I/R injury. We evaluated the potential association between MBL and sC5b-9 in plasma and subsequent cardiac dysfunction in patients with STEMI treated with primary percutaneous coronary intervention (pPCI).

AB - The positive effect of reperfusion after ST-elevation myocardial infarction (STEMI) can be reduced by ischemic/reperfusion (I/R) injury.Mannose-binding-lectin (MBL) and soluble C5b-9 (membrane-attack-complex) are involved in complement-driven cell lysis and may play a role in human myocardial I/R injury. We evaluated the potential association between MBL and sC5b-9 in plasma and subsequent cardiac dysfunction in patients with STEMI treated with primary percutaneous coronary intervention (pPCI).

M3 - Journal article

C2 - 19126922

SN - 1557-2501

VL - 21

SP - 13

EP - 19

JO - The Journal of invasive cardiology

JF - The Journal of invasive cardiology

IS - 1

ER -

Level of complement activity predicts cardiac dysfunction after acute myocardial infarction treated with primary percutaneous coronary intervention

Abstract

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