Lessons from an international trial evaluating vaccination strategies for recovered inpatients with COVID-19 (VATICO)

Eleftherios Mylonakis; Joseph Lutaakome; Mamta K Jain; Angela J Rogers; José Moltó; Susana Benet; Ahmad Mourad; D Clark Files; Henry Mugerwa; Cissy Kityo; Francis Kiweewa; Mary Grace Nalubega; Jonathan Kitonsa; Evelyn Nabenkema; Daniel D Murray; Dominique Braun; Dena Kamel; Elizabeth S Higgs; Timothy J Hatlen; Virginia L Kan; Adriana Sanchez; John Tierney; Eileen Denner; Deborah Wentworth; Abdel G Babiker; Victoria J Davey; Annetine C Gelijns; Gail V Matthews; B Taylor Thompson; H Clifford Lane; James D Neaton; Jens D Lundgren

doi:10.1016/j.medj.2022.07.003

Lessons from an international trial evaluating vaccination strategies for recovered inpatients with COVID-19 (VATICO)

Eleftherios Mylonakis^*, Joseph Lutaakome, Mamta K Jain, Angela J Rogers, José Moltó, Susana Benet, Ahmad Mourad, D Clark Files, Henry Mugerwa, Cissy Kityo, Francis Kiweewa, Mary Grace Nalubega, Jonathan Kitonsa, Evelyn Nabenkema, Daniel D Murray, Dominique Braun, Dena Kamel, Elizabeth S Higgs, Timothy J Hatlen, Virginia L KanAdriana Sanchez, John Tierney, Eileen Denner, Deborah Wentworth, Abdel G Babiker, Victoria J Davey, Annetine C Gelijns, Gail V Matthews, B Taylor Thompson, H Clifford Lane, James D Neaton, Jens D Lundgren

^*Corresponding author af dette arbejde

Afdeling for Infektionssygdomme

2 Citationer (Scopus)

Abstract

The protection provided by natural versus hybrid immunity from COVID-19 is unclear. We reflect on the challenges from trying to conduct a randomized post-SARS-CoV-2 infection vaccination trial study with rapidly evolving scientific data, vaccination guidelines, varying international policies, difficulties with vaccine availability, vaccine hesitancy, and a constantly evolving virus.

Originalsprog	Engelsk
Tidsskrift	Med (New York, N.Y.)
Vol/bind	3
Udgave nummer	8
Sider (fra-til)	531-537
Antal sider	7
ISSN	2666-6340
DOI	https://doi.org/10.1016/j.medj.2022.07.003
Status	Udgivet - 12 aug. 2022

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10.1016/j.medj.2022.07.003

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Mylonakis, E., Lutaakome, J., Jain, M. K., Rogers, A. J., Moltó, J., Benet, S., Mourad, A., Files, D. C., Mugerwa, H., Kityo, C., Kiweewa, F., Nalubega, M. G., Kitonsa, J., Nabenkema, E., Murray, D. D., Braun, D., Kamel, D., Higgs, E. S., Hatlen, T. J., ... Lundgren, J. D. (2022). Lessons from an international trial evaluating vaccination strategies for recovered inpatients with COVID-19 (VATICO). Med (New York, N.Y.), 3(8), 531-537. https://doi.org/10.1016/j.medj.2022.07.003

Mylonakis, E, Lutaakome, J, Jain, MK, Rogers, AJ, Moltó, J, Benet, S, Mourad, A, Files, DC, Mugerwa, H, Kityo, C, Kiweewa, F, Nalubega, MG, Kitonsa, J, Nabenkema, E, Murray, DD, Braun, D, Kamel, D, Higgs, ES, Hatlen, TJ, Kan, VL, Sanchez, A, Tierney, J, Denner, E, Wentworth, D, Babiker, AG, Davey, VJ, Gelijns, AC, Matthews, GV, Thompson, BT, Lane, HC, Neaton, JD & Lundgren, JD 2022, 'Lessons from an international trial evaluating vaccination strategies for recovered inpatients with COVID-19 (VATICO)', Med (New York, N.Y.), bind 3, nr. 8, s. 531-537. https://doi.org/10.1016/j.medj.2022.07.003

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title = "Lessons from an international trial evaluating vaccination strategies for recovered inpatients with COVID-19 (VATICO)",

abstract = "The protection provided by natural versus hybrid immunity from COVID-19 is unclear. We reflect on the challenges from trying to conduct a randomized post-SARS-CoV-2 infection vaccination trial study with rapidly evolving scientific data, vaccination guidelines, varying international policies, difficulties with vaccine availability, vaccine hesitancy, and a constantly evolving virus.",

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AU - Rogers, Angela J

AU - Moltó, José

AU - Benet, Susana

AU - Mourad, Ahmad

AU - Files, D Clark

AU - Mugerwa, Henry

AU - Kityo, Cissy

AU - Kiweewa, Francis

AU - Nalubega, Mary Grace

AU - Kitonsa, Jonathan

AU - Nabenkema, Evelyn

AU - Murray, Daniel D

AU - Braun, Dominique

AU - Kamel, Dena

AU - Higgs, Elizabeth S

AU - Hatlen, Timothy J

AU - Kan, Virginia L

AU - Sanchez, Adriana

AU - Tierney, John

AU - Denner, Eileen

AU - Wentworth, Deborah

AU - Babiker, Abdel G

AU - Davey, Victoria J

AU - Gelijns, Annetine C

AU - Matthews, Gail V

AU - Thompson, B Taylor

AU - Lane, H Clifford

AU - Neaton, James D

AU - Lundgren, Jens D

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AB - The protection provided by natural versus hybrid immunity from COVID-19 is unclear. We reflect on the challenges from trying to conduct a randomized post-SARS-CoV-2 infection vaccination trial study with rapidly evolving scientific data, vaccination guidelines, varying international policies, difficulties with vaccine availability, vaccine hesitancy, and a constantly evolving virus.

KW - COVID-19/prevention & control

KW - COVID-19 Vaccines

KW - Humans

KW - Inpatients

KW - Randomized Controlled Trials as Topic

KW - Vaccination/methods

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JO - Med (New York, N.Y.)

JF - Med (New York, N.Y.)

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ER -

Lessons from an international trial evaluating vaccination strategies for recovered inpatients with COVID-19 (VATICO)

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