TY - JOUR
T1 - Less known aspects of central hypothyroidism
T2 - Part 1 - Acquired etiologies
AU - Benvenga, Salvatore
AU - Klose, Marianne
AU - Vita, Roberto
AU - Feldt-Rasmussen, Ulla
PY - 2018/12
Y1 - 2018/12
N2 - Central hypothyroidism (CH) is a rare cause of hypothyroidism. CH is frequently overlooked, as its clinical picture is subtle and includes non-specific symptoms; furthermore, if measurement of TSH alone is used to screen for thyroid function, TSH concentrations can be normal or even above the upper normal reference limit. Indeed, certain patients are at risk of developing CH, such as those with a pituitary adenoma or hypophysitis, those who have been treated for a childhood malignancy, have suffered a head trauma, sub-arachnoid hemorrhage or meningitis, and those who are on drugs capable to reduce TSH secretion.
AB - Central hypothyroidism (CH) is a rare cause of hypothyroidism. CH is frequently overlooked, as its clinical picture is subtle and includes non-specific symptoms; furthermore, if measurement of TSH alone is used to screen for thyroid function, TSH concentrations can be normal or even above the upper normal reference limit. Indeed, certain patients are at risk of developing CH, such as those with a pituitary adenoma or hypophysitis, those who have been treated for a childhood malignancy, have suffered a head trauma, sub-arachnoid hemorrhage or meningitis, and those who are on drugs capable to reduce TSH secretion.
U2 - 10.1016/j.jcte.2018.09.003
DO - 10.1016/j.jcte.2018.09.003
M3 - Review
C2 - 30416972
SN - 2214-6237
VL - 14
SP - 25
EP - 33
JO - Journal of Clinical and Translational Endocrinology
JF - Journal of Clinical and Translational Endocrinology
ER -