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Less known aspects of central hypothyroidism: Part 2 - Congenital etiologies

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DOI

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Vis graf over relationer

Central hypothyroidism (CH) occurs approximately in 1:50,000, and therefore is expected to be one thousand times rarer compared with primary hypothyroidism. Despite its rarity in the general population, it is much more common in certain disorders, in which it is frequently associated with other pituitary hormone deficiencies. The aim of this paper is to provide an updated review on the frequency of congenital CH, which is <1:50,000, and on its etiology, disregarding CH caused by other genetic defects, such as mutations of transcription factors involved in pituitary organogenesis or mutations of the genes encoding TRH or TRH receptor.

OriginalsprogEngelsk
TidsskriftJournal of Clinical and Translational Endocrinology
Vol/bind14
Sider (fra-til)5-11
Antal sider7
ISSN2214-6237
DOI
StatusUdgivet - dec. 2018

ID: 56291085