LEP promoter methylation in the initiation and progression of clonal cytopenia of undetermined significance and myelodysplastic syndrome

Keyphrases

• Myelodysplastic Syndrome 100%
• Promoter Methylation 100%
• Clonal Cytopenia of Undetermined Significance 100%
• Myeloid Neoplasms 37%
• Healthy Controls 25%
• Obesity 25%
• Overall Survival 25%
• Acute Myeloid Leukemia 25%
• Hypermethylation 25%
• Clonal Cytopenia 25%
• Clinical Outcomes 12%
• High Risk 12%
• Leptin 12%
• Independent Risk Factors 12%
• Anemia 12%
• Patient-controlled 12%
• Elderly People 12%
• Clinical Presentation 12%
• Worse Prognosis 12%
• Serum Leptin 12%
• Leptin Levels 12%
• Poor Prognosis 12%
• DNA Methylation (DNAm) 12%
• Progression-free Survival 12%
• Risk of Progression 12%
• Peripheral Blood 12%
• Blood Cells 12%
• Early Events 12%
• Regulated Genes 12%
• Hematopoietic Cells 12%
• Cytopenia 12%
• Malignant Potential 12%
• Multivariate Cox Regression Analysis 12%
• Hypermethylated 12%
• Aberrant DNA Methylation 12%
• Biological Relationships 12%
• Leukemia Transformation 12%
• Blast Count 12%
• Bone Marrow Blast 12%
• Bone Marrow Dysplasia 12%

Medicine and Dentistry

• Promoter Region 100%
• Cytopenia 100%
• Myelodysplastic Syndrome 100%
• Methylation 100%
• Neoplasm 33%
• Leptin 22%
• Overall Survival 22%
• DNA Methylation 22%
• Acute Myeloid Leukemia 22%
• Disease 11%
• Anemia 11%
• Proportional Hazards Model 11%
• Hematopoietic Stem Cell 11%
• Blood Cell 11%
• Progression Free Survival 11%
• Elderly Population 11%

Biochemistry, Genetics and Molecular Biology

• Promoter Region 100%
• Methylation 100%
• Myeloid 71%
• Leptin 28%
• Overall Survival 28%
• DNA Methylation 28%
• Progression Free Survival 14%
• Hemocyte 14%
• Dysplasia 14%