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Length of life gained with surgical treatment of prostate cancer- A population-based analysis.

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@article{56a45e9682534893a97e912dcc479936,
title = "Length of life gained with surgical treatment of prostate cancer- A population-based analysis.",
abstract = "OBJECTIVE: The aim of this study was to analyse relative survival, excess mortality and gain in life expectancy in men who underwent radical prostatectomy (RP) for localized prostate cancer (PCa) between 1995 and 2011 in Denmark.MATERIAL AND METHODS: The study population comprised the complete cohort of 6489 men who underwent RP between 1995 and 2011. Risk of mortality was calculated using a competing risk model. Relative survival, excess mortality rate (EMR) and gain in life expectancy in men undergoing RP were calculated using a matched cohort Danish population based on date of birth and date of surgery.RESULTS: During follow-up 328 patients died, 109 (33.2{\%}) of PCa and 219 (66.8{\%}) of other causes. The cumulative incidence of PCa mortality was 5.8{\%} [95{\%} confidence interval (CI) 4.4, 7.2] after 10 years. Relative survival was significantly above 1.0 for RP patients, except for high-risk patients. EMR was -9.34 (95{\%} CI -10.56, -8.13) after 10 years, i.e. nine men would die in excess of the general population. Overall, the gain in life expectancy in men undergoing RP compared with the general population was 0.41 years.CONCLUSION: This population-based study demonstrated that the gain in life expectancy with RP compared with the general population in Denmark is minimal.",
author = "R{\o}der, {Martin Andreas} and Klaus Brasso and Ea Rusch and J{\o}rgen Johansen and Langkilde, {Niels Christian} and Helle Hvarness and Steen Carlsson and Henrik Jakobsen and Michael Borre and Peter Iversen",
year = "2015",
doi = "10.3109/21681805.2014.984324",
language = "English",
volume = "49",
pages = "275--81",
journal = "Scandinavian Journal of Urology",
issn = "2168-1805",
publisher = "Taylor & Francis",
number = "4",

}

RIS

TY - JOUR

T1 - Length of life gained with surgical treatment of prostate cancer- A population-based analysis.

AU - Røder, Martin Andreas

AU - Brasso, Klaus

AU - Rusch, Ea

AU - Johansen, Jørgen

AU - Langkilde, Niels Christian

AU - Hvarness, Helle

AU - Carlsson, Steen

AU - Jakobsen, Henrik

AU - Borre, Michael

AU - Iversen, Peter

PY - 2015

Y1 - 2015

N2 - OBJECTIVE: The aim of this study was to analyse relative survival, excess mortality and gain in life expectancy in men who underwent radical prostatectomy (RP) for localized prostate cancer (PCa) between 1995 and 2011 in Denmark.MATERIAL AND METHODS: The study population comprised the complete cohort of 6489 men who underwent RP between 1995 and 2011. Risk of mortality was calculated using a competing risk model. Relative survival, excess mortality rate (EMR) and gain in life expectancy in men undergoing RP were calculated using a matched cohort Danish population based on date of birth and date of surgery.RESULTS: During follow-up 328 patients died, 109 (33.2%) of PCa and 219 (66.8%) of other causes. The cumulative incidence of PCa mortality was 5.8% [95% confidence interval (CI) 4.4, 7.2] after 10 years. Relative survival was significantly above 1.0 for RP patients, except for high-risk patients. EMR was -9.34 (95% CI -10.56, -8.13) after 10 years, i.e. nine men would die in excess of the general population. Overall, the gain in life expectancy in men undergoing RP compared with the general population was 0.41 years.CONCLUSION: This population-based study demonstrated that the gain in life expectancy with RP compared with the general population in Denmark is minimal.

AB - OBJECTIVE: The aim of this study was to analyse relative survival, excess mortality and gain in life expectancy in men who underwent radical prostatectomy (RP) for localized prostate cancer (PCa) between 1995 and 2011 in Denmark.MATERIAL AND METHODS: The study population comprised the complete cohort of 6489 men who underwent RP between 1995 and 2011. Risk of mortality was calculated using a competing risk model. Relative survival, excess mortality rate (EMR) and gain in life expectancy in men undergoing RP were calculated using a matched cohort Danish population based on date of birth and date of surgery.RESULTS: During follow-up 328 patients died, 109 (33.2%) of PCa and 219 (66.8%) of other causes. The cumulative incidence of PCa mortality was 5.8% [95% confidence interval (CI) 4.4, 7.2] after 10 years. Relative survival was significantly above 1.0 for RP patients, except for high-risk patients. EMR was -9.34 (95% CI -10.56, -8.13) after 10 years, i.e. nine men would die in excess of the general population. Overall, the gain in life expectancy in men undergoing RP compared with the general population was 0.41 years.CONCLUSION: This population-based study demonstrated that the gain in life expectancy with RP compared with the general population in Denmark is minimal.

U2 - 10.3109/21681805.2014.984324

DO - 10.3109/21681805.2014.984324

M3 - Journal article

VL - 49

SP - 275

EP - 281

JO - Scandinavian Journal of Urology

JF - Scandinavian Journal of Urology

SN - 2168-1805

IS - 4

ER -

ID: 45853464