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Leitlinien für diagnostik und therapie in der neurologie: Prophylaxe der migräne mit monoklonalen antikörpern gegen CGRP oder den CGRP-rezeptor

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. Erenumab prevents the occurrence of migraine attacks and not just migraine days: Post-hoc analyses of a phase III study

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  3. Onset of action in placebo-controlled migraine attacks trials: A literature review and recommendation

    Publikation: Bidrag til tidsskriftReviewForskningpeer review

  4. Pharmacological strategies to treat attacks of episodic migraine in adults

    Publikation: Bidrag til tidsskriftReviewForskningpeer review

  • Hans Christoph Diener
  • Stefanie Förderreuther
  • Charly Gaul
  • Florian Giese
  • Till Hamann
  • Dagny Holle-Lee
  • Tim P. Jürgens
  • Katharina Kamm
  • Torsten Kraya
  • Christian Lampl
  • Arne May
  • Uwe Reuter
  • Armin Scheffler
  • Peer Tfelt-Hansen
Vis graf over relationer

Monoclonal antibodies against the calcitonin gene-related peptide (CGRP) receptor (erenumab) or against CGRP (eptinezumab, fremanezumab, galcanezumab) are new substances for the preventive treatment of migraine. They represent an extension of the therapeutic options which already exist in migraine prevention. In registration studies, the efficacy and good tolerability of these specific substances have been demonstrated in patients with episodic and chronic migraine. The following treatment recommendation presents a summary of the pivotal studies. Recommendations are given for the targeted selection of patients as well as for the evaluation of therapeutic success and the duration of treatment. Finally, possible restrictions in the use of this new substance group are discussed.

Bidragets oversatte titelGuidelines for diagnosis and therapy in neurology: Prevention of migraine with monoclonal antibodies against CGRP or the CGRP receptor. Supplement to the guideline 030/057 for the therapy of migraine attacks and prevention of migraine
OriginalsprogTysk
TidsskriftArzneimitteltherapie
Vol/bind38
Udgave nummer3
Sider (fra-til)69-92
Antal sider24
ISSN0723-6913
StatusUdgivet - 1 jan. 2020

ID: 60061994